Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The following key studies including 2 study reports have been selected to determinate the acute toxicity of 1-bromo-3-chloropropane :
- acute oral toxicity in the rat (Denton S.M.)
- acute dermal toxicity in the rat (Denton S.M.)
- characteristics of the General Toxic, Gonadatropic, and Mutagenic Effects of 1,3-chlorobromopropane (Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv)

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
1 100 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
7.27 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

Justification for classification or non-classification

Under the experimental conditions, 1-bromo-3-chloropropane does require labelling with the hazard statement H302 "Harmful if swallowed" and H331 "Toxic if inhaled" in accordance with the CLP regulation.