1-(carboxylatomethyl)methylpyridinium

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

from 2018-01-03 to 2018-02-17

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: CIPAC Handbook Volume F, MT 3.2, "Determination of Specific Gravity or Density of Liquids or Solids"

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Key result

Type:

relative density

Density:

1.488 other: dimensionless

Temp.:

20 °C

Table 1. Determination of water equivalent and volume at 20 ºC

Replicate	Weight of Empty Pycnometer (x) (g)	Weight of Pycnometer with Water (y) (g)	Water Equivalent Weight (y-x) (g)	Volume of the Pycnometer at 20 °C (mL) V20= (y-x)/0.998 mL
1	42.9247	92.8263	49.9016	50.0016
2	41.7293	91.6320	49.9027	50.0027

 

Table 2. Determination of density of wetting solution

Replicate	Weight of Empty Pycnometer (x’)(g)	Weight of Pycnometer with Wetting Solution (y’) (g)	Weight of Wetting Solution (y’-x’) (g)	Volume of Pycnometer (mL) at 20 °C	Density of Wetting Solution (y’-x’)/V (g/mL)
1	42.9247	98.1040	55.1793	50.0016	1.1036
2	41.7293	95.9868	54.2575	50.0027	1.0851

 

Table 3. Determination of volume of wetting solution

Replicate	Weight of Empty Pycnometer (g)	Weight of Pycnometer with Test Item and Wetting Solution (g)	Weight of Pycnometer with Test Item (g)	Weight of Test Item (g)	Volume of Wetting Solution (mL)
1	42.9247	105.8678	73.0740	30.1493	29.7153
2	41.7293	104.6966	73.7855	32.0562	28.4869

 

Table 4. Determination of relative density of the test item

Replicate	Weight of Test Item (g)	Volume of Pycnometer (mL)	Volume of Wetting Solution (mL)	Density of Test Item (g/mL)	Mean Density (g/mL)	(±) SD	RSD (%)
1	30.1493	50.0016	29.7153	1.4862	1.4881	0.003	0.20
2	32.0562	50.0027	28.4869	1.4899

 SD = Standard Deviation, RSD = Relative Standard Deviation

Conclusions:

The relative density of the test item was determined to be 1.4881 at 20 °C.

Executive summary:

A study was conducted according to OECD TG 109, Regulation (EC) No 440/2008 method A.3, OPPTS 830.7300 and CIPAC Handbook Volume F, MT 3.2 to determine the relative density of the test item. Using Tween 80 as wetting solution the volume of the pycnometer and the density of the weting solution were determined. Using these results, the density of the test item was determined in duplicate. Using the pycnometer method the density was determined to be 1.4881 ± 0.0030 g/cm³ at 20 ± 0.5 °C and the relative density 1.4881 with respect to water at 4 °C, respectively.

Description of key information

The relative density of the test item was determined to be 1.4881 at 20 °C.

Key value for chemical safety assessment

Relative density at 20C:

1.488

Additional information

A study was conducted according to OECD TG 109, Regulation (EC) No 440/2008 method A.3, OPPTS 830.7300 and CIPAC Handbook Volume F, MT 3.2 to determine the relative density of the test item. Using Tween 80 as wetting solution the volume of the pycnometer and the density of the weting solution were determined. Using these results, the density of the test item was determined in duplicate. Using the pycnometer method the density was determined to be 1.4881 ± 0.0030 g/cm³ at 20 ± 0.5 °C and the relative density 1.4881 with respect to water at 4 °C, respectively.