Resin acids and Rosin acids, maleated, esters with glycerol

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

June 2016-December 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Study is well documented and performed in line with standard guidelines. Study done to GLP.

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Specific details on test material used for the study:

Identification: Resin acids and Rosin acids, maleated, esters with glycerol
CAS Number: 94581-16-5
Appearance/Physical state: yellow solid
Batch Number: 168000
Purity: 100%
Expiry: 01 March 2017
Storage conditions: Approximately 4°C, in the dark

Key result

Water solubility:

< 0.001 g/L

Conc. based on:

test mat.

Incubation duration:

> 24 - < 72 d

Temp.:

20 °C

pH:

> 4.99 - < 5.72

Details on results:

Preliminary Test: The preliminary estimate of the water solubility was less than 2.16 x 10-2 g/L.
Definitive Test: On completion of the equilibration period, some samples were clear and colorless with excess test item present.  Other samples were either hazy or opaque in colour with excess test item present. The solutions were filtered.  After filtration, the supernatant was taken for analysis. The supernatant was visually observed to be clear/colorless and free from un-dissolved test item (no Tyndall beam present). As the test item was essentially insoluble in water, the column elution method should have been performed.  However, as the test item is a complex mixture, the column elution method is deemed to be of little use. Testing by the flask method maximises solubility and is more suitable for test items that are mixtures.  In addition, the test item contains ester functionalities and as such, expected to hydrolyse under environmentally relevant conditions. The column elution test is a longer equilibration time from the flask method and if performed, any hydrolysis would prevent the true water solubility being determined.  Therefore, in this case it was considered more appropriate to test using the flask method. It was considered more appropriate to perform analyses using TOC rather than applying a substance specific analytical method.  This was again due to the complex nature of the test item and the issues that would be encountered attempting to quantify each individual component. It can be seen from the individual results that the concentration of organic carbon in the blank solutions is similar to that in the sample solutions indicating that the test item is essentially insoluble in water.  The instrument has a limit of detection of approximately 1 mg/L and therefore based on the low amounts found in each of the sample solutions, it was considered more appropriate to use 1 mg/L as the limit value.

Table 2. Total Organic Carbon (TOC) relating to the standard and sample solutions.

Solution	TOC (mg/l)
Sample Blank 1	0.636
Sample 1A	0.723
Sample 1B	0.494
Sample 2A	0.990
Sample 2B	0.272
Sample Blank 2	0.474
Sample 3A	0.885
Sample 3B	0.407
Sample 4A	1.05
Sample 4B	0.711
Sample Blank 3	0.569
Sample 5A	0.831
Sample 5B	0.494
Sample 6A	1.03 x 10^3*
Sample 6B	1.02 x 10^3*

* Not used in overall result.

Table 3. Concentration of test item in sample solutions.

Sample Number	Time shaken at ~30 °C (hours)	Concentration (g/l)	Solution pH
1	72	<1 x 10^-3	5.28
2	72	<1 x 10^-3	5.59
3	48	<1 x 10^-3	5.51
4	48	<1 x 10^-3	5.61
5	24	<1 x 10^-3	5.72
6	24	n/a	4.99

Conclusions:

The water solubility of the test item was determined to be 1.00 x 10-3 g/l of solution at 20 ± 0.5 °C.

Executive summary:

The water solubility of Resin acids and Rosin acids, maleated, esters with glycerol was determined by the flask method according to OECD guideline 105. The water solubility of the test item was determined to be 1.00 x 10^-3 g/L of solution at 20 ± 0.5°C.

Description of key information

The water solubility of esters of maleated rosin with glycerol was determined by the flask method according to OECD guideline 105. The water solubility of the test item was determined to be 1.00 x 10^-3g/L of solution at 20 ± 0.5 °C.

Key value for chemical safety assessment

Water solubility:

0.001 g/L

at the temperature of:

20 °C