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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 233-271-0 | CAS number: 10102-43-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Interacting effects of pH acclimation, pH, and heavy metals on acute and chronic toxicity to Ceriodaphnia dubia (Cladocera)
- Author:
- Belanger SE and Cherry DS
- Year:
- 1 990
- Bibliographic source:
- Journal of Crustacean Biology, 10(2): 225-235.
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Principles of method if other than guideline:
- Daphnids reared in pH 8.0
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Nitric acid
- EC Number:
- 231-714-2
- EC Name:
- Nitric acid
- Cas Number:
- 7697-37-2
- Molecular formula:
- HNO3
- IUPAC Name:
- nitric acid
Constituent 1
- Specific details on test material used for the study:
- HNO3 is degradation product of NO in water so this study expresses the aquatic toxicity of NO.
Sampling and analysis
- Analytical monitoring:
- not specified
- Remarks:
- indirect: pH measurement
Test solutions
- Vehicle:
- yes
- Remarks:
- test material Nitric acid was supplied as a 1% solution (in water presumably)
Test organisms
- Test organisms (species):
- Ceriodaphnia dubia
- Details on test organisms:
- Ceriodaphnia dubia were obtained from US EPA Duluth stock in 1984 from T.J. Norberg and were cultured in water from New River (Virginia).
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 98 mg/L
- Test temperature:
- 25°C
- pH:
- Two tests were conducted at nominal pH values of 3.0, 4.0, 5.0, 6.0, 7.0, 8.0, 9.0, 10.0, 11.0, and 12.0 to determine the pH LC50. pH was adjusted using HNO3
- Nominal and measured concentrations:
- see pH
Results and discussion
Effect concentrations
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 4.6 other: pH
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: pH
- Basis for effect:
- mortality
- Details on results:
- Ceriodaphnia dubia cultured at pH 8.0 suffered 100% mortality at pH 3.2-3.4. The individual 48-h LC50s for acidic pH were 4.4 and 4.7. Grand probits (analyses combined) were 4.6 for acid pH.
Applicant's summary and conclusion
- Conclusions:
- Ceriodaphnia dubia cultured at pH 8.0 suffered 100% mortality at pH 3.2-3.4. The 48-h LC50 was pH=4.6.
HNO3 is degradation product of NO in water so this result expresses the aquatic toxicity of NO.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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