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Diss Factsheets
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EC number: 412-830-4 | CAS number: 1823-59-2 ODPA
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: QSAR calculation, acceptable with restrictions
- Justification for type of information:
- 1. SOFTWARE: EPI Suite TM - EPIWEB 4.11
2. MODEL: BIOWIN V4.10
3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL: O=C1OC(=O)c2ccc(cc12)Oc3cc4c(cc3)C(=O)OC4(=O) - Principles of method if other than guideline:
- Biowin v4.10 in EPISuite 4 (2009). The Biodegradation Probability Program (Biowin) estimates the probability for the rapid aerobic biodegradation of an organic chemical in the presence of mixed populations of environmental microorganisms. Estimates are based upon fragment constants that were developed using multiple linear and non-linear regression analyses.
- GLP compliance:
- no
- Remarks:
- Not applicable
- Specific details on test material used for the study:
- SMILES : O=C1OC(=O)c2ccc(cc12)Oc3cc4c(cc3)C(=O)OC4(=O)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: Not applicable
- Details on inoculum:
- Not applicable
- Details on study design:
- Not applicable
- Preliminary study:
- Not applicable
- Test performance:
- Not applicable
- Remarks on result:
- other: QSAR predicted value and results can be found in the "details on results" field
- Details on results:
- Probability of Rapid Biodegradation (BIOWIN v4.10):
Biowin1 (Linear Model) : 0.7318 (Biodegrades fast)
Biowin2 (Non-Linear Model) : 0.7010 (Biodegrades fast)
Expert Survey Biodegradation Results:
Biowin3 (Ultimate Survey Model) : 2.4555 (weeks-months)
Biowin4 (Primary Survey Model) : 3.4773 (days-weeks)
MITI Biodegradation Probability:
Biowin5 (MITI Linear Model) : 0.0338 (Not readily Degradable)
Biowin6 (MITI Non-Linear Model) : 0.0123 (Not readily Biodegradable)
Anaerobic Biodegradation Probability:
Biowin7 (Anaerobic Linear Model) : 0.4115 (Does not Biodegrade Fast)
Ready Biodegradability Prediction : NO - Results with reference substance:
- Not applicable
- Validity criteria fulfilled:
- not applicable
- Remarks:
- QSAR
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The results of BIOWin predictions indicate that the test substance is not readily biodegradable
- Executive summary:
The use of a QSAR to predict the biodegradability of the test substance and the use of Biowin is an appropriate technique to use as the test substance falls within the applicability domain of the model.
Reference
BIOWIN predicted that the test substance is not readily biodegradable.
Description of key information
The results of BIOWin predictions indicate that the test substance is not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Biowin v4.10 in EPISuite 4 (2009). The Biodegradation Probability Program (Biowin) estimates the probability for the rapid aerobic biodegradation of an organic chemical in the presence of mixed populations of environmental microorganisms. Estimates are based upon fragment constants that were developed using multiple linear and non-linear regression analyses.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.