Registration Dossier
Registration Dossier
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EC number: 248-655-3 | CAS number: 27776-21-2
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07-11 September 2015
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Solutions of the test item in water are agglutinated. So it was not possible to prepare a satured and filterable solution. The test item and water were mixed in different ratios to cover the range of complete miscibility. The mixtures were agitated on a roller mixer or on a shaking machine at T = 23 °C overnight and after that conditioned at 20 °C ± 0.5 °C overnight.
The solubility range is between the lowest concentration with undissolved test item and the highest observed concentration with completely dissolved test item. - GLP compliance:
- yes (incl. QA statement)
- Type of method:
- other: The method is described in "Principles of method if other than guideline".
- Key result
- Water solubility:
- > 200 - < 300 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- ca. 1 d
- Temp.:
- 20 °C
- pH:
- >= 3.5 - <= 3.8
- Conclusions:
- Based on visual inspection the solubility of the substance in water is between the lowest observed concentration with completely dissolved test item (200 g/L) and the highest concentration with undissolved test item (300 g/L).
Reference
Description of key information
The solubility of the substance in water is between the lowest observed concentration with completely dissolved test item (200 g/L) and the highest concentration with undissolved test item (300 g/L). For the chemical safety assessment, the lower limit is used.
Key value for chemical safety assessment
- Water solubility:
- 200 g/L
- at the temperature of:
- 20 °C
Additional information
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