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Diss Factsheets
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EC number: 205-167-5 | CAS number: 134-96-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 998
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- - Principle of test:
- Short description of test conditions:
- Parameters analysed / observed: - GLP compliance:
- no
Test material
- Reference substance name:
- 4-hydroxy-3,5-dimethoxybenzaldehyde
- EC Number:
- 205-167-5
- EC Name:
- 4-hydroxy-3,5-dimethoxybenzaldehyde
- Cas Number:
- 134-96-3
- Molecular formula:
- C9H10O4
- IUPAC Name:
- 4-hydroxy-3,5-dimethoxybenzaldehyde
- Test material form:
- not specified
- Details on test material:
- Solved in Ethanol. Source: Sigma Chemical Co.
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Details on test solutions:
- Compound purity was compensated for when preparing stock solutions. Test solutions were prepared in tenfold concentration increments, and four replications were used for each concentration and control.
Test organisms
- Test organisms (species):
- Oscillatoria sp.
- Details on test organisms:
- Oscillatoria cf. chalybea, isolated from a west-central Mississippi cattish production pond (van der Ploeg et al. 1995)
Unialgal cultures were grown and maintained in continuous, steady-states at 29°C under continuous light by the method of van der Ploeg et al. (1995) except that light intensity was 18-29 μE/m /sec and air flow rate was 16-33 L/hr. Cell density in the continuous cultures was maintained at 0.18-0.27 A (absorbance) for O. cf. chalybea, 0.19-0.26 A for S. capricornutum, 0.28-0.33 A for Anabaena sp. LP 691, and 0.20-0.24 A for P. simplex. Cell density was measured at 750 nm using a Gilford model Response UV-VIS spectrophotometer (Gilford Instrument Laboratories, Inc., Oberlin, OH).
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 5 d
Test conditions
- Test temperature:
- 25-27°C
- Nominal and measured concentrations:
- 1, 10, 100 and 1000 μM
- Details on test conditions:
- A rapid microtiter plate-based assay developed previously for screening compounds for selectivity as cyanobacterial algicides was used (Schrader et al. 1997).
Microplates were placed in a growth chamber at 25-27°C and illuminated by three overhead fluorescent lamps (40 W, cool white) at a light intensity of 20-28
2 μE/m /sec. Optical densities of each well were measured daily for 5 d at 650 nm using a Packard model Spectracount microplate photometer (Packard Instrument Company, Meriden, CT).
Results and discussion
Effect concentrations
- Key result
- Duration:
- 5 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 100 µmol/L
- Nominal / measured:
- nominal
- Basis for effect:
- growth rate
Applicant's summary and conclusion
- Conclusions:
- The LOEC for Oscillatoria cf. chalybea growth was 100 μM.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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