Registration Dossier
Registration Dossier
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EC number: 700-150-3 | CAS number: 156572-81-5
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- GLP compliance:
- yes
- Type of method:
- HPLC estimation method
- Media:
- soil
- Test temperature:
- 25°C
- Details on study design: HPLC method:
- EQUIPMENT
- Apparatus: Hewlett Packard 1200 Series Liquid Chromatograph
- Column: Hypersil CPS (25 cm x 4.6 mm internal diameter)
MOBILE PHASES
- Type: Acetonitrile:water (55:45 v/v)
- pH: Since the test substance was anticipated to be in its ionised form (sulphonate functionality)over the entire pH range of environmental relevance (approximately 4 to 9), the test system was not buffered at a specific pH value.
- Solutes for dissolving test and reference substances:
REFERENCE SUBSTANCES
- Identity: acetanilide
- Type:
- Koc
- Value:
- < 20
- Temp.:
- 25 °C
- Type:
- log Koc
- Value:
- < 1.3
- Temp.:
- 25 °C
- Details on results (HPLC method):
- The retention time of SLMI was shorter than that of acetanilide, the lowest available reference standard recommended by the test guidelines. indicating log10Koc value of less than 1.3 (Koc < 20).
- Validity criteria fulfilled:
- yes
- Conclusions:
- Pureact SLMI-85 was determined to have a log10 Koc value of less than 1.3 (Koc < 20).
Reference
As the sorption behaviour of the test substance was investigated using HPLC, the nature of the column allows for interaction of polar and apolar parts of a molecule in a similar way to soil. As soil was not used, there was no organic carbon content to measure.
Description of key information
In a study performed to OECD 121, SLMI was determined to have a log10 Koc value of less than 1.3 (Koc < 20).
Key value for chemical safety assessment
- Koc at 20 °C:
- 20
Additional information
In a study performed to OECD 121, SLMI was determined to have a log10 Koc value of less than 1.3 (Koc <20)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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