2-(4-methylcyclohex-3-en-1-yl)propan-2-ol

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 15 to 29 June 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Well described study performed according to GLP and OECD guideline 102 without any deviation

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Type of method:

capillary method

Key result

Melting / freezing pt.:

>= -35.9 - <= -28.2 °C

Remarks on result:

other: Standard deviation (SD): 0.14 (begin) and 0.28 (end); estimated accuracy: ± 0.4 °C

Table 1: Values in pre-test

Room Temperature	5 °C	-20 °C	-80 °C
liquid	liquid	slightly frozen	solid

 

Table 2: Melting values in main study

Melting point/range	Begin	End
First determination	-36.0 °C (237.2 K)	-28.4 °C (244.8K)
Second determination	-35.8 °C (237.4 K)	-28.0 °C (245.2K)

Table 3: Validity

 

Parameter	Criterion	Found	Assessment
Difference between duplicate determinations	≤ 5.0K	0.4 K	valid
Difference between begin and end of melting process	≤ 5.0K	7.7 K	melting range is stated

Conclusions:

The melting range of terpineol multiconstituent was determined to be -35.9 to -28.2 °C (237.3 to 245 K).

Executive summary:

A GLP study was conducted to determine the melting range of terpineol multiconstituent by capillary/metal block method according to OECD Guideline 102 and EU Method A.1. The melting ranges during the first and second measurements were estimated to be -36 to -28.4 °C and -35.8 to -28.0 °C, respectively. The estimated accuracy was ± 0.4 °C.

 

The melting range of terpineol multiconstituent was determined to be -35.9 to -28.2 °C (237.3 to 245 K).

Description of key information

The melting range of terpineol multiconstituent was determined by capillary/metal block method.
The melting range of terpineol multiconstituent was determined to be -35.9 to -28.2 °C (237.3 to 245 K).

Additional information

Key study conducted according to OECD 102 and EU A.1 guideline, under GLP without deviation and with certificate of analysis included. Therefore the result of the key study is proposed as end point value.