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EC number: 201-044-5 | CAS number: 77-62-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 23 June 2015 to 10 September 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- European Community (EC), EC no. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.4: “Vapour Pressure", Official Journal of the European Union no. L220, August 24, 2009.
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no.104: "Vapour Pressure", March 23, 2006.
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Version / remarks:
- United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7950: "Vapor pressure", August 1996.
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- effusion method: isothermal thermogravimetry
- Specific details on test material used for the study:
- Identification: 2,2'-methylenebis[6-(1-methylcyclohexyl)-p-cresol]
Appearance: White to cream powder
Batch: WWP4J0001
Purity/Composition: 92.2%
Test substance storage: At room temperature
Stable under storage conditions until: 03 September 2018 (retest date)
Purity/composition correction factor: Yes, correction factor is according to purity
Test substance handling: No specific handling conditions required - Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Temp.:
- 20 °C
- Vapour pressure:
- 0 mm Hg
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Temp.:
- 25 °C
- Vapour pressure:
- 0 mm Hg
- Conclusions:
- ≤ 5.8 e-7 Pa; ≤ 4.3 e-9 mm Hg at 20°C
≤ 1.3e-6 Pa; ≤ 9.7e-9 mm Hg at 25°C - Executive summary:
The aim of the study was to determine the physico-chemical properties for 2,2'-methylenebis[6-(1-methylcyclohexyl)-p-cresol].
The study was based on the following guidelines:
European Community (EC), EC no. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.4: “Vapour Pressure", Official Journal of the European Union no. L220, August 24, 2009.
Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no.104: "Vapour Pressure", March 23, 2006.
United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7950: "Vapor pressure", August 1996.
The isothermal TGA effusion method was applied for the determination of the vapour pressure of 2,2'-methylenebis[6-(1-methylcyclohexyl)-p-cresol]. The weight losses of the test substance were obtained at temperatures above the melting temperature of the test substance because no significant weight loss of the test substance was observed below the melting temperature. According to this, the vapour pressure at 20°C and 25°C might be overestimated.
The vapour pressure of the test substance at 20°C (293K) and 25°C (298K) was therefore reported as equal or less than values:
20°C
25°C
[Pa]
[mm Hg]
[Pa]
[mm Hg]
Test substance
≤ 5.8 x 10-7
≤ 4.3 x 10-9
≤ 1.3 x 10-6
≤ 9.7 x 10-9
Reference
The equation of the curve was: log PT= -6104 x 1/T + 14.58 (r = 0.9997, n = 8).
Results of the isothermal TGA analysis
Temperature [°C] |
Weight loss [μg/min] |
vT [g/cm2/h] |
Log vT |
Log PT |
PT [Pa] |
170 |
4.295 4.543 |
5.13 x 10-4 5.42 x 10-4 |
-3.29 -3.27 |
0.80 0.83 |
6.3 6.7 |
180 |
7.825 7.966 |
9.34 x 10-4 9.51 x 10-4 |
-3.03 -3.02 |
1.10 1.11 |
13 13 |
190 |
14.03 13.99 |
1.67 x 10-3 1.67 x 10-3 |
-2.78 -2.78 |
1.40 1.40 |
25 25 |
200 |
24.55 24.56 |
2.93 x 10-3 2.93 x 10-3 |
-2.53 -2.53 |
1.69 1.69 |
49 49 |
Vapour pressure of the test substance
Temperature [°C] |
Log PT |
PT [Pa] |
PT [mm Hg] |
20
25 |
-6.24
-5.89 |
5.8 x 10-7
1.3 x 10-6 |
4.3 x 10-9
9.7 x 10-9 |
Description of key information
Key value determined in a GLP accredited laboratory study using the isothermal TGA effusion method, performed in accordance with EU MEthod A.4, OECD Guideline 104 and US EPA Procedure OPPTS 830.7950.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
The isothermal TGA effusion method was applied for the determination of the vapour pressure of 2,2'-methylenebis[6-(1-methylcyclohexyl)-p-cresol]. The weight losses of the test substance were obtained at temperatures above the melting temperature of the test substance because no significant weight loss of the test substance was observed below the melting temperature. According to this, the vapour pressure at 20°C and 25°C might be overestimated.
The vapour pressure of the test substance at 20°C (293K) and 25°C (298K) was therefore reported as equal or less than values:
|
20°C |
25°C |
||
[Pa] |
[mm Hg] |
[Pa] |
[mm Hg] |
|
Test substance |
≤ 5.8 x 10-7 |
≤ 4.3 x 10-9 |
≤ 1.3 x 10-6 |
≤ 9.7 x 10-9 |
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