Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- Due to the UVCB nature of the substance, the OECD guideline is slightly modified to account for that. The modifications are outlined in the field “principles of method if other than guideline”
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- Deviation from Guideline OECD 105:
OECD 105 allows to determine the water solubility of pure compounds. In a mixture or multi-constituent substance, every constituent has its own solubility which may differ from the solubility of the others. The solubility of a mixture in total can therefore only be estimated from the point, a significant amount of the sample is no longer soluble. Due to the fact that usually no standard compounds are available for the mixture constituents, the dissolved amount of the sample has to be determined using a suitable sum-parameter method (e.g. total organic carbon) related to the total content of the sum-parameter in the sample (e.g. in this case carbon). - GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- ca. 4 g/L
- Temp.:
- 20 °C
- pH:
- 5.4 - 6.1
- Conclusions:
- The water solubility of the test item in demineralized water is estimated to be approx. 4 g/L at 20 °C and pH 5.4 - 6.1. It classifies as: soluble (1000-10000 mg/L)
- Executive summary:
The water solubility of the test item in demineralized water is estimated to be approx. 4 g/L at 20 °C and pH 5.4 - 6.1. The test substance contains approx. 10 % insoluble parts in demineralized water. (CURRENTA, 2009).
Reference
Description of key information
The water solubility of the test item in demineralized water is estimated to be approx. 4 g/L at 20 °C and pH 5.4 - 6.1. The test item contains approx. 10 % insoluble parts in demineralized water. (Currenta, 2009).
Key value for chemical safety assessment
- Water solubility:
- 4 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
