Registration Dossier
Registration Dossier
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EC number: 281-692-3 | CAS number: 84012-52-2
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
Not Mutagenic
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Ames test in on going and expected to be negative.
Justification for classification or non-classification
According to the CLP Regulation (EC n. 1272/2008), for the purpose of classification for germ cell mutagenicity, substances are allocated to one of two categories:
CATEGORY 1
Substances known to induce heritable mutations or to be regarded as if they induce heritable mutations in the germ cells of humans.
Substances known to induce heritable mutations in the germ cells of humans.
CATEGORY 2
Substances which cause concern for humans owing to the possibility that they may induce heritable mutations in the germ cells of humans.
The classification in Category 2 is based on positive evidence obtained from experiments in mammals and/or in some cases from in vitro experiments.
Based on the experimental results and on the ECHA Guidance R7.a, Figure R.7.7-1, the substance is considered as not genotoxic and no classification for germ cell mutagenicity is warranted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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