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Diss Factsheets
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EC number: 402-030-3 | CAS number: 624-86-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study with analytical monitoring
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 987
- Report date:
- 1987
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- O-ethylhydroxylamine
- EC Number:
- 402-030-3
- EC Name:
- O-ethylhydroxylamine
- Cas Number:
- 624-86-2
- Molecular formula:
- C2 H7 N O
- IUPAC Name:
- O-ethylhydroxylamine
- Details on test material:
- - Name of test material (as cited in study report): Substance H109360 & Q125
- Physical state: colourless liquid
- Analytical purity: 50%
- Lot No.: EFI-100
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: A stock solution of the test substance was prepared ín dilution water. 1 L of each test solution was prepared by the addition of aliquots of stock solution to dilution water.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Source: obtained from continous laboratory cultures
- Age at study initiation: < 24 h
- Feeding during test: no
HOUSING
- Culture medium: a reconstituted water medium, identical to the test dilution water
- Temperature: 20 ± 2 °C
- Type and amount of food: defined diet of algae (Chlorella vulgaris) and yeast
- Photoperiod: 16 hours light : 8 hours dark
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 162 mg/L as CaCO3
- Test temperature:
- 19.6 - 20.8 °C
- pH:
- 8.2 - 8.6
- Dissolved oxygen:
- 9.0 -9.25 mg/L
- Nominal and measured concentrations:
- Nominal test concentrations: control, 1, 1.8, 3.2, 5.6, 10, 18 mg/L
Recovery rate of the test substance in the stock solution: 101%; test solutions were not analysed, since the estimated detection limit was 100 mg/L - Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Material, fill volume: Borosilicate glass beakers, 200 ml
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: reconstituted water medium aerated for >2 h
- Alkalinity: 111 mg/L
- Conductivity: 482 µS/cm
- Intervals of water quality measurement: Dissolved oxygen the control was measured prior to the start of the test. Initial pH was determined of each test solution. At the end of the test the pH and dissolved oxygen concentration of two replicates of each control and treatment were measured. The temperature of water was measured in an additional at 0, 24 and 48 h.
OTHER TEST CONDITIONS
- Photoperiod: 16 h light :8 h darkness
EFFECT PARAMETERS MEASURED: mobility after 24 and 48 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 2.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: Testsolution with a water content of 50%
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% CL: 2.3 - 2.9 mg/L
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1.3 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- other: pure substance
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% CL: 1.1 - 1.5 mg/L
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.