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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From October 31, 1989 to November 02, 1989
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
No analytical verification of test concentrations
Qualifier:
according to guideline
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
Daphnia magna
Details on test organisms:
Age: 2 - 24 hours
Light/Dark: 8/16 hours
Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
48 h
Hardness:
2.77 mmol/L
Test temperature:
19.5 - 20.8°C
pH:
8.1
Dissolved oxygen:
> 2 mg/L
Nominal and measured concentrations:
Nominal: 0, 7.8, 15.6, 31.3, 62.5, 125, 250 and 500 mg/L
Details on test conditions:
Test volume: 10 mL (with 5 animals per test volume)
Number of animals per concentration: 20
Reference substance (positive control):
no
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 500 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
EC0
Effect conc.:
7.8 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
EC100
Effect conc.:
> 500 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Conclusions:
Under the study conditions, the 48h EC0, 50, and 100 (in terms of swimming mobility) were determined to be 7.813, > 500, and > 500 mg test material/L (nominal), respectively.
Executive summary:

A study was conducted to determine the toxicity of the test substance (in the form of a 200 mg/L dispersion) to aquatic invertebrates (Daphnia magna) according to EU Method C.2. The Daphnia were exposed for 48 h at concentrations up to 500 mg/L under static conditions. The swimming mobility was assessed after 0, 3, 6, 24 and 48 h. No analytical monitoring of test concentrations was conducted. Under the study conditions, the 48 h EC0, 50 and 100 were determined to be 7.813, > 500 and > 500 mg test material/L (nominal), respectively (Jatzek, 1989).

Description of key information

Key value for chemical safety assessment:

EC50/LC50 for freshwater invertebrates: > 500 mg/L (test material; purity not given)

EC50/LC50 for freshwater invertebrates: -

Key value for chemical safety assessment

Additional information

A study was conducted to determine the toxicity of the test substance (in the form of a 200 mg/L dispersion) to aquatic invertebrates (Daphnia magna) according to EU Method C.2. The Daphnia were exposed for 48 h at concentrations up to 500 mg/L under static conditions. The swimming mobility was assessed after 0, 3, 6, 24 and 48 h. No analytical monitoring of test concentrations was conducted. Under the study conditions, the 48 h EC0, 50 and 100 were determined to be 7.813, > 500 and > 500 mg test material/L (nominal), respectively (Jatzek, 1989).