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Diss Factsheets
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EC number: 432-070-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- October 1997 - November 1997
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
PHYSICO-CHEMICAL PROPERTIES
- Melting point: no melting point/range (Decomposition at temperatures > 200 °C)
- Boiling point: no boiling point (decomposition before boiling)
- Vapour pressure: <1 * 10-12 hPa at 25°C (calculation)
- Water solubility: 125.76 g/L at 20°C
- log Pow: <-2
- pKa: = 7,00+/-0,04 - Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 600 mg/L, 1250 mg/L, 2500 mg/L, 5000 mg/L, 10000mg/L
- Vehicle:
- yes
- Details on test solutions:
- The test article is a well soluble powder with strongly reducing properties. A stock solution was made up with 20 L aerated tap-water (c:10g/L). This solution was aerated until the oxygen saturation was >=80%. Prior to the test this solution was diluted with aerated tap-water
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- Brachydanio rerio: 7 animals/concentration (10 L per vessel)
water: de-chlorinated tap water
supplier: Aquarium Stahl, Rangendingen
Pre-treatment: none (the animaly were held in the laboratory for at leas 12 days before testing; mortality: 0%)
light: 14 h light, 10 h dark , illumination: 60-Watt Gro-Lux
areation: permanent with pasteur pipettes
feeding: no feeding during the test
size: 3.1-3.5 cm
weight: 0.27 - 0.39 g
corpulence factor 0.9 -0.91 g/cm³ [G(g) x 100 /L(cm³)] - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Post exposure observation period:
- 96 h
- Hardness:
- Carbonate hardness: 8 mg CaCO3/L
total hardness: 8.6 °dH - Test temperature:
- 23°C +/- 2°C
- pH:
- 7.9 - 8.4
- Dissolved oxygen:
- > 80% in all vessels at various observation times (0h, 24h, 48h, 72h, 96h)
- Salinity:
- de-chlorinated tap-water;
Nitrate: 3 mg/L;
Nitrite: <0.1 mg/L;
Zn: 0.8 mg/L;
Fe/Cd/Pb/Cu/Ni:<0.1 mg/L - Nominal and measured concentrations:
- see table 1
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 20 L solid-glass fish tanks
- Aeration: Pasteur pipettes, pump
- No. of animals per concentration: 7
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: tap-water
- Metals:Zn: 0.8 mg/L; Fe/Cd/Pb/Cu/Ni:<0.1 mg/L
- Chlorine: dechlorined water - Reference substance (positive control):
- yes
- Duration:
- 24 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 7 400 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 7 400 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- > 7 400 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 5 000 mg/L
- Details on results:
- OBSERVATIONS:
-swarm behaviour
-activity
-surfacing
-balance
-mortalities
-gills (breathing-frequency)
-600 mg/L: After 96 h the animals behave as in the control
-2500 mg/l: analogue 600 mg/L
-5000 mg/l: analogue 600 mg/L
-10000 mg/l: after 72 h one animal died. After 96 h the surviving animals behave as in the control - Results with reference substance (positive control):
- - Mortality: 0
see table 2 - Sublethal observations / clinical signs:
table 2: Cumulative mortality [%] at various observation times
time [h] control 600 [mg/L] 1250 [mg/L] 2500 [mg/l] 5000 [mg/L] 10000 [mg 24 0 0 0 0 0 0 48 0 0 0 0 0 0 72 0 0 0 0 0 14 .3 96 0 0 0 0 0 14.3 - Validity criteria fulfilled:
- yes
- Conclusions:
- The test substance is not acute toxic to fish.
LC50 (96h) >7400 mg/l
Reference
Description of key information
Not acute toxic to fish.
LC50 (96h) >7400 mg/l
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 7 400 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.