Registration Dossier
Registration Dossier
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EC number: 204-846-3 | CAS number: 127-51-5
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Data is from secondary source
- Qualifier:
- according to guideline
- Guideline:
- other: as mentioned below
- Principles of method if other than guideline:
- Estimation of hydrolysis half-life of test chemical in river and lake water using the Bond SAR method.
- GLP compliance:
- not specified
- Radiolabelling:
- not specified
- Analytical monitoring:
- not specified
- Estimation method (if used):
- Bond SAR method
- Positive controls:
- not specified
- Negative controls:
- not specified
- Transformation products:
- not specified
- Key result
- DT50:
- 8.655 h
- Remarks on result:
- other: in river water
- Key result
- DT50:
- 168.9 h
- Remarks on result:
- other: in lake water, half-life: 168.9 hrs (7 days)
- Details on results:
- The half-life of test chemical in river and lake water was estimated to be 8.655 hrs and 168.9 hrs (7 days), respectively.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The half-life value of test chemical in river and lake water was estimated to be 8.655 hrs and 168.9 hrs (7 days), respectively. Thus based on the value, test chemical is considered to undergoe moderate to slow hydrolysis in water.
- Executive summary:
The half-life of the test chemical was estimatedusing the Bond SAR method.The half-life value of test chemical in river and lake water was estimated to be 8.655 hrs and 168.9 hrs (7 days), respectively. Thus based on the value, test chemical is considered to undergoe moderate to slow hydrolysis in water.
Reference
Description of key information
The half-life of the test chemical was estimatedusing the Bond SAR method (secondary source, 2017).The half-life value of test chemical in river and lake water was estimated to be 8.655 hrs and 168.9 hrs (7 days), respectively. Thus based on the value, test chemical is considered to undergoe moderate to slow hydrolysis in water.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 7 d
- at the temperature of:
- 25 °C
Additional information
The half-life of the test chemical was estimatedusing the Bond SAR method (secondary source, 2017).The half-life value of test chemical in river and lake water was estimated to be 8.655 hrs and 168.9 hrs (7 days), respectively. Thus based on the value, test chemical is considered to undergoe moderate to slow hydrolysis in water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
