Registration Dossier
Registration Dossier
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EC number: 211-016-4 | CAS number: 627-89-4
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No chronic toxic effects on aquatic invertebrates up to the limit of water solubility, read across.
Key value for chemical safety assessment
Additional information
Data on the chronic toxicity of Isopentyl oleate (CAS 627-89-4) to aquatic invertebrates is not available. The assessment was therefore based on a study conducted with the structurally similar substance Isobutyl oleate (CAS 84988-79-4) as part of a read across approach, which is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Further justification is given within the overall summary chapter 6.1 and within the analogue justification section 13.
The chronic toxicity of the source substance Isobutyl oleate (CAS
84988-79-4) to Daphnia magna was tested according to OECD 202 (Wierich,
1995). A semi-static test system with nominal test substance
concentrations of 1 and 100 mg/L was set up at 1 and 100 mg/L (nominal).
No mortality or adverse effects on the reproduction rate of D. magna
were observed. At test termination after 21 d a NOELR (21 d) ≥ 100 mg/L
based on the reproduction was observed.
Based on the available result from one structurally related source
substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5)
which is characterized by a similar ecotoxicological profile and
comparable structure, it can be concluded that Isopentyl oleate (CAS
627-89-4) will not exhibit long-term effects to aquatic invertebrates up
to the limit of water solubility.
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