PIGMENT ROT 5021 A

Hydrolysis

Administrative data

Endpoint:

hydrolysis

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

03.12.1991

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: None GLP guideline study. However, the test could not be performed as the water solubility of the test substance is lower than 1 x 10E-4 g/L.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1991

Report date:

1991

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: 84/449/EEC, A.6

Deviations:

no

GLP compliance:

no

Test material

Test material information

Constituent 1

Specific details on test material used for the study:

Details on properties of test surrogate or analogue material (migrated information):
Not applicable.

Radiolabelling:

no

Study design

Analytical monitoring:

no

Details on sampling:

Not applicable.

Results and discussion

Details on results:

The hydrolysis test could not be performed.

Any other information on results incl. tables

The hydrolysis test could not be performed due to following reasons:

The water solubility of the test substance is lower than 1 x 10E-4 g/L. The detection limit of the analytical method must be at least 40 times lower and the factor of 40 is due to the fact that:

- The initial concentration for the hydrolysis test must not exceed half the saturation concentration.

- the accuracy of the analytical method should be better than 5% of the initial concentration (e.g. to determine a 10% decomposition during the preliminary test).

For this reasons and because only the upper limit of the water solubility was experimentally determinable, the hydrolysis test could not be performed.