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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The Effective concentration (EC50) for Thiosemicarbazide was found to be 12 mg/L in a 48 hr study conducted on Daphnids on the basis of effect on mobility.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
12 mg/L

Additional information

Short-term toxicity test to aquatic invertebrates was conducted to study the effects of thiosemicarbazide. The Dose concentration used is 12mg/l for 48 hours. Based on Mortality median lethal dose (LC50) was considered to be 12mg/l for thiosemicarbazide .

Based on the value and biodegradability status, the substance may be classified in aquatic chroniccategory 3 as per the CLP regulation.