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EC number: 247-640-9 | CAS number: 26381-41-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Appearance
In a opinion given by Scientific Committee on Consumer Safety for Basic Brown 16 (2012), a study report by COLIPA mentioned that the Basic Brown 16 is odourless Dark green to black coloured organic solid powder.
Melting point:
On the basis of prediction using Danish QSAR modelling database (2016), Melting point of test substance [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride was estimated to be 280.11 deg C.
In a opinion given by Scientific Committee on Consumer Safety for Basic Brown 16 (2012), a study report by COLIPA mentioned that the Basic Brown 16 melted at 169-175 °C.
Based on the above available value, Melting point of test substance [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride was estimated to be 280.11 deg C.
Boling point:
On the basis of prediction using Danish QSAR modelling database (2016), Boling point of substance [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride was estimated to be 644.52°C
Density:
In a Santa Cruz Biotechnology (2016), density of Basic brown 16 was found to be ~1.2 g/cm3
Particle size distribution
In a study conducted by Sustainability Support Service (Europe) AB has letter of access (2016), particle size distribution of test item Basic brown 16 (CAS No. 26381-41-9) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was found to be in the range of 150 micron to 10 micron.
Vapour pressure:
On the basis of prediction using Danish QSAR modelling database (2016), Vapour pressure of substance [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride was estimated to be 0.00000000000006319 Pa.It is reported as 0.000000001 Pa for the chemical safety assessment due to the limitation in the field.
Partition coefficient:
On the basis of prediction using Danish QSAR modelling database (2016), Partition coefficient of test substance [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride was estimated to be log Kow =0.88.
In a opinion given by Scientific Committee on Consumer Safety for Basic Brown 16 (2012), a study report by COLIPA mentioned that Partition coefficient of Basic Brown 16 by EU Method A.8 was found to be log Kow = -0.74 at 23°C and pH 9.95.
On the basis of above available data, Partition coefficient of [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride were log Kow =0.88.
Water solubility:
On the basis of prediction using Danish QSAR modelling database (2016), Water solubility of test substance [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride was estimated to be 2281 mg/L. This solubility value indicated that test substance is soluble in water.
In a opinion given by Scientific Committee on Consumer Safety for Basic Brown 16 (2012), a study report by COLIPA mentioned that water solubility of Basic Brown 16 was 3730 mg/L at 20°C.
On the basis of above available value, Basic Brown 16 was water soluble in the range of 2281 to 3730 mg/L at 20°C.
Surface tension:
In accordance with column 2 of Annex VII of the REACH regulation, the study need only be conducted if surface activity is a desired property of the chemical. The chemical [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride(Common Name: Basic brown 16) is used as a hair color. For this uses, surface activity is not an important property. Hence this study was considered for waiver.
Flash point:
In a Material safety data sheet of Look chem Flash point of Basic brown 16 was found to be 398.1 °C.
Auto flammability
The chemical [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride (Common Name: Basic brown 16) does not catch fire upon exposure to air at normal conditions of temperature and pressure. Thus the chemical is not likely to be "Auto flammable" and hence this end point was considered for waiver.
Flammability:
The chemical [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride(Common Name: Basic brown 16) has an NFPA rating of 1 for Flammability. Thus the chemical is not likely to be "Flammable" under normal conditions of use, storage and transportation and hence this end point was considered for waiver.
Explosiveness:
In accordance with column 2 of Annex VII of the REACH regulation, the study does not need to be conducted since there are no chemical groups associated with explosive properties present in the molecule of [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride (Common Name: Basic brown 16), except the Azo group. Thus, the chemical is likely to be "Non explosive". Hence this end point was considered for waiver
Oxidising property:
In accordance with column 2 of Annex VII of the REACH regulation, the substance [8-[(p-aminophenyl)azo]-7-hydroxy-2-naphthyl]trimethylammonium chloride (Common Name: C.I. 12250) is incapable of reacting exothermically with combustible materials on the basis of the chemical structure. It is an organic substance not containing oxygen but chloride atom and these elements are not chemically bonded to nitrogen or oxygen. Thus, the chemcial is likely to be "Non-oxidising".
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