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EC number: 436-690-9 | CAS number: 220727-26-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Study period:
- 2001
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Expert statement with an accepted estimation method
- Qualifier:
- according to guideline
- Guideline:
- other: Lyman, Reehl, Rosenblatt: Handbook of chemical property estimation methods, 1990
- Principles of method if other than guideline:
- The estimation was performed based on the octanol/water partition coefficient of log Kow > 4.2 using a regression equation and relating the Koc with Kow.
- GLP compliance:
- no
- Remarks:
- calculation
- Type of method:
- other: calculation
- Media:
- soil
- Radiolabelling:
- no
- Type:
- Koc
- Value:
- >= 4 590
- Type:
- log Koc
- Value:
- >= 3.66
- Conclusions:
- Y-15099 has a high potential to adsorb to soil particles indicated by a Koc of = 4590.
- Executive summary:
An estimation of the absorption coefficient is available for this test substance based on the calculated log Kow and using a regression analysis equation (Lyman, Reehl, Rosenblatt: Handbook of chemical property estimation methods, 1990). The result (Koc: 4590 or higher) indicates that binding to soil is an important sorption method. Y-15099 is well absorbed to soil and is therefore considered to be immobile. This means there is little risk of it leaching into deeper soils.
Reference
The adsorption coefficient (Koc) of Y-15099 was estimated to be 4590 or higher and would be classified as immobile in soils.
The mobility classification was obtained by comparing the calculated Koc value to the mobility classes according to Guth (International Symposium, Canterbury, 1 -3 July 1985, Adsorption/Desorption).
Range of Koc |
Mobility Class |
> 1725 |
I Immobile |
< 1725 to > 172 |
II Little mobile |
< 172 to > 86 |
III Moderately mobile |
<86 to > 34 |
IV Slightly mobile |
< 34 to > 17 |
V Mobile |
< 17 |
VI Very mobile |
Description of key information
log Koc: = 3.6 for Y-15099 and 0.02 - 2.46 (MCI method) for the hydrolysis products
Key value for chemical safety assessment
- Koc at 20 °C:
- 4 590
Additional information
An estimation of the adsorption coefficient is available for Y-15099 (CAS 220727-26-4). The estimation is based on the calculated log Kow (> 4.2) and using a regression analysis equation relating the Koc with the Kow, according to Lyman, Reehl and Rosenblatt (Handbook of chemical property estimation methods, 1990). The estimated Koc = 4590 (log Koc of = 3.6) indicates that binding to soil and sediment particles is an important sorption method, with Y-15099 being well absorbed to soil and sediment and is thus immobile (Völkel, 2001).
But since the substance is hydrolytically unstable the expected hydrolysis products should be considered when evaluating the adsorption potential. Since no data are available for the hydrolysis products, the log Koc was calculated by KOCWIN v3.20 (Müller, 2012). The results indicate a low potential for adsorption to soil and sediment particles based on calculated log Koc values of 0.02 - 2.46. For the ethanol hydrolysis product an experimental log Koc value of 0.2 can also be found in the EPISuite database which is in line with the calculated value of 0.02 indicating a low potential for adsorption.
[LogKoc: 3.6]
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