DL-serinohydrazide monohydrochloride

Auto flammability

Administrative data

Endpoint:

relative self-ignition temperature (solids)

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Justification for type of information:

See further information in the cross-ref.

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

self-heating substances / mixtures

Type of information:

experimental study

Adequacy of study:

key study

Study period:

01 October 2014-08 January 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.4 (Test method for self-heating substances)

Version / remarks:

UN ST/SG/AC.10/11/Rev.5: Recommendations on the Transport of Dangerous Good
s, Manual of Tests and Criteria, Part III Section 33.3.1 "Substances liable to spontaneous
combustion” (2009).

Deviations:

no

GLP compliance:

yes

Test procedure:

100 mm sample cube at 140°C

Max. temp. reached:

291

Result:

positive outcome (effect observed)

Remarks on result:

other: After the experiment, the test substance had turned into a expanded black charred residue

Test procedure:

25 mm sample cube at 140°C

Result:

negative outcome (no effect observed)

Remarks on result:

other:

Remarks:

After the experiment, the test substance had turned into a expanded beige brown residue

Test procedure:

100 mm sample cube at 120°C

Result:

negative outcome (no effect observed)

Remarks on result:

other:

Remarks:

After the experiment, the test substance had turned into a off white residue

In the test performed at 140 ± 2°C using a 10 cm sample cube, an exothermic effect of the test substance by self-heating was observed between 16-21 hours. During this effect the test substance reached a maximal temperature of 291°C. According to the guideline, the test is positive when the sample temperature exceeds the oven temperature by 60°C during 24 hour testing time. Based on this, the result is considered positive. After the experiment, the test substance had turned into a expanded black charred residue.

In the test performed at 140 ± 2°C using a 2.5 cm sample cube, no spontaneous ignition occurred and no exothermic effect of the test substance was observed during the entire test period. Therefore this test was considered negative. After the experiment, the test substance had turned into a expanded beige brown residue.

In the test performed at 120 ± 2°C using a 10 cm sample cube, no spontaneous ignition occurred and no exothermic effect of the test substance was observed during the entire test period. Therefore this test was considered negative. After the experiment, the test substance had turned into a off white residue.

Interpretation of results:

not classified based on GHS criteria

Conclusions:

In a GLP-compliant study performed in accordance with UN-MTC Section 33.3.1 (Test N.4), a positive result was obtained using a 100 mm sample cube at 140°C, a negative result was obtained with a 25 mm sample cube at 140°C and a negative result is obtained with a 100 mm sample cube at 120°C. It was concluded that the test substance is considered a self-heating substance when tested in a 10 cm sample cube at 140°C.