Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Health surveillance data

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Administrative data

Endpoint:
health surveillance data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Published study not reviewed. Abstract and information from a third party review included for information and completion purposes only.

Data source

Reference
Reference Type:
publication
Title:
Male alcohol consumption and fecundity in couples attending an infertility clinic.
Author:
Dunphy BC, Barratt CL, Cooke ID.
Year:
1991
Bibliographic source:
Andrologia; 23: 219–21.

Materials and methods

Study type:
medical monitoring
Endpoint addressed:
toxicity to reproduction / fertility
Principles of method if other than guideline:
Evaluation of the relationship between male alcohol intake and fertility from couples attending an infertility clinic.

Test material

Constituent 1
Reference substance name:
Alcoholic beverages
IUPAC Name:
Alcoholic beverages

Method

Type of population:
general
Details on study design:
Population: 258 couples
Categorisation of alcohol intake: <1 unit/week, 1-5 units, 6-10 units, 11-20 units, >20 units/week.

Results and discussion

Results:
No association between the amount of alcohol and sperm parameters was observed in this study. In addition, there was no significant difference
in the alcohol intake between normal and abnormal female groups. There was no significant association between the amount of alcohol consumed per week and the fertility outcome.

Applicant's summary and conclusion