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Diss Factsheets
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EC number: 270-109-8 | CAS number: 68411-20-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Performing of a BCF study with this complex substance is considerd to be technically not feasible. However a QSAR for the final product of the hydrolys and especially the hydrolysis in the presence of light, 3-ethyl-4-propyl-quinoline yielded an estimated BCF of 596 L/kg wwt (logBCF= 2.77). This result indicates that the final product of butanal reaction products with aniline in water does not meet the B criterion.
Key value for chemical safety assessment
Additional information
It has been demonstated in the waiving statements that the substance is not only complex and contains a high number of components, but it is also not stable in water and has a complex reaction pattern in water.
A search in the ECHA database and other public databases as well as in REACH guidance documents did not lead to examples or guidances for BCF studies performed with UVCB substances. The Registrant is aware that this item is currently under discussion in expert groups, e.g. from CEFIC and ECHA. As a BCF study is consuming animals, the Registrant is willing performing of a such study (after having stated a study proposal) if an adequate and scientifically found study design is available which allows the proper determination of a BCF value.
Having the B criterion in focus, a more detailed analysis of the hydrolysis products will be performed which also allows to fully compare the analysis of the UVCB substance "butanal, reaction products with aniline" (via GC-MS) with the analytical method performed on the hydrolysis products (LC-MS). After further analytical characterization of relevant compounds the corresponding BCFs will be estimated via QSAR with an accepted calculation method and correlated with the abiotic and/or biotic degradation properties of the respective compound.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.