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EC number: 202-905-8 | CAS number: 100-97-0
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1964
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only data from publication available
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Handbook data only. No guideline or method indicated.
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Water solubility:
- 897.9 g/L
- Temp.:
- 0 °C
- pH:
- >= 7 - <= 9
- Water solubility:
- 869.2 g/L
- Temp.:
- 25 °C
- pH:
- >= 7 - <= 9
- Water solubility:
- 818.2 g/L
- Temp.:
- 50 °C
- pH:
- >= 7 - <= 9
- Details on results:
- not applicable
- Conclusions:
- Very soluble (> 10000 mg/L)
The water solubility of methenamine is 47.3 % w/w (897.9 g/L) at 0 °C, 46.5 % w/w (869.2 g/L) at 25 °C and 45.0 % w/w (818.2 g/L) at 50 °C. The pH value ranges from 7 to 9. Thus, the substance is regarded to be very soluble in water. - Executive summary:
The water solubility of methenamine is 47.3 % w/w (897.9 g/L) at 0 °C, 46.5 % w/w (869.2 g/L) at 25 °C and 45.0 % w/w (818.2 g/L) at 50 °C. The pH value ranges from 7 to 9. Thus, the substance is regarded to be very soluble in water. Solubility decreases slightly with increasing temperature.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1949
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only handbook data available
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Handbook data only. No guideline or method indicated.
- Type of method:
- other: no data
- Water solubility:
- 81.3 vol%
- Temp.:
- 12 °C
- pH:
- >= 7 - <= 9
- Details on results:
- 81.3 g of the substance are soluble in 100 g water at 12 °C
- Conclusions:
- very soluble (> 10000 mg/L)
According to the handbook data 81.3 g of methenamine are soluble in 100 g water (=> 813.0 g/L) at 12 °C and a pH range from 7 to 9 . Thus, the substance is regarded to be very soluble in water. - Executive summary:
According to the handbook data 81.3 g of methenamine are soluble in 100 g water (=> 813.0 g/L) at 12 °C and a pH range from 7 to 9. Thus, the substance is regarded to be very soluble in water.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1999
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: company data without indication of test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Handbook data only. No guideline or method indicated.
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Water solubility:
- 89.5 vol%
- Temp.:
- 20 °C
- pH:
- >= 7 - <= 9
- Water solubility:
- 87.4 vol%
- Temp.:
- 40 °C
- pH:
- >= 7 - <= 9
- Water solubility:
- 84.4 vol%
- Temp.:
- 60 °C
- pH:
- >= 7 - <= 9
- Details on results:
- vol% = g/100 g Wasser
- Conclusions:
- very soluble (> 10000 mg/L)
According to the company data the water solubility of methenamine is 89.5 g/100 g (~ 895 g/L) at 20 °C, 87.4 g/100 g (~ 874 g/L) at 40 °C and 84.4 g/100 g (~ 844 g/L) at 60 °C. The pH value ranges from 7-9. Thus, the substance is regarded to be very soluble in water. - Executive summary:
According to the company data the water solubility of methenamine is 89.5 g/100 g (~ 895 g/L) at 20 °C, 87.4 g/100 g (~ 874 g/L) at 40 °C and 84.4 g/100 g (~ 844 g/L) at 60 °C. The pH value ranges from 7-9. Thus, the substance is regarded to be very soluble in water. Solubility decreases slightly with increasing temperature.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1985
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only handbook-data available
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Handbook data only. No guideline or method indicated.
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Water solubility:
- 813 g/L
- Temp.:
- 12 °C
- pH:
- >= 7 - <= 9
- Details on results:
- solubility decreases slightly with increasing temperature
- Conclusions:
- Very soluble (> 10000 mg/L)
The water solubility of methenamine was determined to 813 g/L at a water temperature of 12 °C and a pH range of 7-9. Thus, the substance is regarded to be very soluble in water. - Executive summary:
According to the handbook-data the water solubility of methenamine was determined to 813 g/L at a water temperature of 12 °C and a pH range of 7-9. Thus, the substance is regarded to be very soluble in water. Solubility decreases slightly with increasing temperature
Referenceopen allclose all
0°C: 47.3 % w/w => 897.5 g/L
25 °C: 46.5 % w/w => 869.2 g/L
50 °C: 45.0 % w/w => 818.2 g/L
no remarks
no remarks
no remarks
Description of key information
According to 2 different handbook data, the water solubility of methenamine was found to be 813.0 g/L (813000 mg/L) at 12 °C and pH 7-9. Thus, the substance is regarded to be highly soluble in water (> 10000 mg/L). The solubility decreases slightly with increasing temperature.
Key value for chemical safety assessment
- Water solubility:
- 813 000 mg/L
- at the temperature of:
- 12 °C
Additional information
Weight of evidence approach:
2 different handbooks show the same value for water solubility (813.0 g/L at 12 °C and pH 7 -9) . This value is thus regarded as reliable.
Other values taken from publication and company data were measured at different temparatures and summarized in the table below.
According to these values, the water solubility of methenamine decreases slightly with increasing temperature, which further support the value used as reference figure at 12°C.
Temperature |
Water solubility |
Data source |
0 °C |
897.5 g/L (47.3 % w/w) |
ACS Monograph, 1964 |
20 °C |
895.0 g/L |
INEOS, 1999 |
25 °C |
869.2 g/L (46.5 % w/w) |
ACS Monograph, 1964 |
40 °C |
874.0 g/L |
INEOS, 1999 |
50 °C |
818.2 g/L (45.0 % w/w) |
ACS Monograph, 1964 |
60 °C |
844.0 g/L |
INEOS, 1999 |
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