Registration Dossier

Administrative data

Description of key information

The only study available is an oral LD50 study on 2,2'-(Octadec-9-enylimino)bisethanol  CAS No 25307-17-9, the study is reliability 1 GLP compliant to OECD Guideline 410.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
1 260 mg/kg bw

Additional information

The only study available is an oral LD50 study on 2,2'-(Octadec-9-enylimino)bisethanol CAS No 25307-17-9. The study is reliability 1 GLP compliant to OECD Guideline 410. We have no data for acute skin toxicity but due to the corrosive nature of the substance it is not ethical to carry out this study. The corrosive classification of the 2,2'-(Octadec-9 -enylimino)bisethanol and the required risk management methods with minimise the potential for skin contact, so the lack of a dermal LD50 will not affect the safe handling of the substance.

2,2'-(Octadec-9-enylimino)bisethanol is a liquid with a low vapour pressure, exposure to vapours would be negligble at ambient temperatures, and aerosol exposure is only expected for dilute solutions du to the corrosive nature of the substance, so the lack of an inhalation LD50 is not considered significant. Based on the viscosity being 147 mPa.s at 20ºC and a density of 0.907 g/cm3 the Kinematic viscosity would be 151 mm2/s. It is therefore unlikely the Kinematic viscosity would be less than 20.5 mm2/s at 40ºC, therefore an aspiration hazard is not expected.

Justification for classification or non-classification

The only study available is an oral LD50 study on 2,2'-(Octadec-9-enylimino)bisethanol CAS No 25307-17-9, the study is reliability 1 GLP compliant to OECD Guideline 410.

The LD Value of 1260 mg/kg is considered correct and will lead to CLP Category 4 for acute oral toxicity.