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EC number: 266-039-2 | CAS number: 65997-03-7 The low boiling fraction obtained by the distillation of tall oil. Contains fatty acids such as palmitic, stearic, oleic and linoleic as well as neutral materials.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
No irritation/corrosion data are available for Tall Oil Heads. However, good quality, reliable data are available for the two related substances Crude Tall Oil (CAS 8002-26-4) and Tall Oil Pitch (CAS 8016-81-7). A weight of evidence approach is therefore used to fill data gaps for Tall Oil Heads.
Crude Tall Oil was found to be not irritant to rabbit skin and eyes in reliable studies conducted according to the appropriate OECD test guidelines and in compliance with GLP (Wolf, 2005). In the key skin irritation study (ARC, 2005b), Tall Oil Pitch was not irritant to rabbit skin. The test was conducted in accordance with OECD 404 and in compliance with GLP. Mean scores for erythema and oedema at 24, 48 and 72 hours were all zero.
In the key eye irritation study (Sanders, 2010), Tall Oil Pitch was not irritant to rabbit eyes. The test was conducted in accordance with OECD 405 and in compliance with GLP. Minimal conjunctival redness was seen up to the 24 hour observation. There were no corneal or iridial effects. Both treated eyes appeared normal by the 48 hour observation.
It can therefore be concluded that Tall Oil Heads is not irritant to rabbit skin and eyes.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
No irritation/corrosion data are available for Tall Oil Heads. Reliable skin and eye irritation studies are, however, available for the related substances Crude Tall Oil (CAS 8002 -26 -4) and Tall Oil Pitch (8016 -81 -7).
Tall Oil Heads is obtained by physical separation (distillation) of Crude Tall Oil, and the two substances are multiconstituent products containing the same constituents in different proportions (the main categories being fatty acids, resin acids, sterols and other neutrals). Tall Oil Heads contains a higher proportion of fatty acids and neutrals (excluding sterol-type constituents, which are not present in Tall Oil Heads), whereas Crude Tall Oil contains a higher proportion of resin acids and sterols.
Tall Oil Pitch is also a product of the distillation of Crude Tall Oil, and contains a higher proprtion of neutrals (sterols and others) than either Crude Tall Oil or Tall Oil Heads, as well as fatty acids, resin acids and a significant proportion of polymeric acids and neutrals.
The results of skin and eye irritation studies with Crude Tall Oil and Tall Oil pitch gave clear negative results for both endpoints in tests according to the relevant OECD test guidelines and in compliance with GLP. No adverse effects were recorded for either substance. These two substances contain all constituents present in Tall Oil Heads at concentrations covering the range that is relevant for the registered substance. It is therefore considered appropriate to take a weight of evidence approach and conclude that Tall Oil Heads is not irritating to rabbit skin and eyes.
Effect level: empty Endpoint conclusion: Adverse effect observed
Justification for classification or non-classification
Based on reliable in vivo skin and eye irritation data for two related substances, it can be concluded that Tall Oil Heads does not meet the criteria for classification as irritant according to EU Directive 67/548/EEC and Regulation 1272/2008.
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