Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 246-466-0 | CAS number: 24800-44-0
Endpoint summary
Administrative data
Description of key information
Additional information
Based on a combination of test data tripropylene glycol presents a low hazard concern for the aquatic environment.
One non-GLP compliant guideline study (OECD 203) is available for tripropylene glycol. The 96-h LC50 value is >1,000 mg/l (nominal concentration) in Oryzias latipes in a semi-static test. One non-GLP compliant guideline study (OECD 202) is available for tripropylene glycol. The 24-h EC50 value is > 1,000 mg/l (nominal concentration) in Daphnia magna in a static test. One non-GLP compliant guideline study (OECD 202) is available for tripropylene glycol. The 21-d NOEC value is >1,000 mg/l (nominal concentration) in Daphnia magna in a semi-static test. One non-GLP compliant guideline study (OECD 201) is available for tripropylene glycol. The 72-h EbC50 value and 72-h NOEbC value is >1,000 mg/l (nominal concentration) in Pseudokirchnerella subcapitata (reported as Selenastrum capricornutum) (OECD, 1994).
In an OECD209 test, the 3h-EC50 was > 1000 mg/L (nominal) and the 3h-NOEC was 1000 mg/L (Harlan Laboratoried, Ltd., 2010).
Long-term exposure of fish is not considered relevant as the substance is readily biodegradable. Based on the fact that the short-term toxicity test shows very low toxicity to fish, the experimental 21d-NOEC to Daphnia magna is >1000 mg/l (OECD, 1994) and the QSAR for long-term toxicity to fish is high (30-d ChV is 1631 mg/l), chronic toxicity to fish is not expected. Therefore, the long-term toxicity test with fish is not considered necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
