Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2006
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable study report which meets basic scientific principles

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2006
Report Date:
2006

Materials and methods

Principles of method if other than guideline:
Determination of solubility in water saturated octanol and in octanol saturated water and calculation of log Pow
Type of method:
other: calculation
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
159
Temp.:
24 °C
pH:
ca. 7
Type:
log Pow
Partition coefficient:
2.2
Temp.:
24 °C
pH:
ca. 7
Details on results:
Pow and log Pow were calculated from the solubilities in octanol saturated water and water saturated octanol (see below)

Any other information on results incl. tables

The following solubilities were obtained:

- Solubility in octanol saturated water: mean 18.8 µg/L (sigma = 2.3, individual values: 17.2, 17.8 and 21.4 µg/L)

- Solubility in water saturated octanol: mean 2980 µg/L (sigma = 0.05, individual values: 2930, 2990 and 3030 µg/L)

These solubilities are used to calculate Pow with the following equation:

Pow = solubility in water saturated octanol / octanol saturated water

Pow = 2980 µg/L / 18.8 µg/L

Pow = 159

log Pow = 2.2

This value is based on measurements taken at 24 -25°C (24°C entered above)

Applicant's summary and conclusion

Conclusions:
The test substance has a log Pow of 2.2.
Executive summary:
The log Pow of the test substance Pigment Violet 19 was calculated from the solubilities in octanol saturated water and in water saturated octanol. The log Pow at 24 -25°C was 2.2.