Registration Dossier
Registration Dossier
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EC number: 234-454-8 | CAS number: 12004-35-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
No data for short-term toxicity to fish are available for the test substance Nickel aluminate. However, there are reliable data available for different structurally analogue test substances.
The environmental fate pathways and ecotoxicity effects assessments for Ni metal and Ni compounds is based on the observation that adverse effects to aquatic, soil- and sediment-dwelling organisms are a consequence of exposure to the bioavailable Ni-ion, released by the parent compound. The result of this assumption is that the ecotoxicology will be similar for all soluble Ni substances used in the ecotoxicity experiments. Therefore, data from soluble nickel substances are used in the derivation of ecotoxicological and environmental fate endpoints, based on the Ni-ion.
Freshwater:
From the database of acute toxicity to freshwater fish, there are 31 high quality studies. This represents 21 different freshwater fish species, dominated by Pimephales promelas, Oncorhynchus mykiss, and Cyprinus carpio. The 96h LC50s values range from 0.23 mg Ni/L (Pimphales promelas; Hoang et al., 2004) to 320 mg Ni/L (Brachydanio rerio; NiPERA, 1993).
Marine:
From the database of acute toxicity to marine fish, there are 4 high quality studies. This represents 3 different marine fish species. The 96h LC50s values range from 26.6 mg Ni/L (Atherinops affinis; Hunt et al., 2002) to 350 mg Ni/L (Fundulus heteroclitus; Eisler and Hennekey, 1977).
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