3-chloropropane-1,2-diol

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

(Q)SAR

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Data from a validated QSAR application toolbox, developped by the OECD.

Justification for type of information:

QSAR prediction: migrated from IUCLID 5.6

Data source

Reference

Reference Type:

other: QSAR toolbox

Title:

OECD QSAR application toolbox v 1.1.02

Author:

OECD

Year:

2008

Bibliographic source:

Organization for Economic Co-operation and Development (OECD), Paris, France.

Materials and methods

Principles of method if other than guideline:

Estimation by using the OECD QSAR Application toolbox

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

3-chloropropane-1,2-diol

EC Number:

202-492-4

EC Name:

3-chloropropane-1,2-diol

Cas Number:

96-24-2

Molecular formula:

C3H7ClO2

IUPAC Name:

3-chloropropane-1,2-diol

Results and discussion

Effect concentrations

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

9 580 mg/L

Nominal / measured:

estimated

Conc. based on:

test mat.

Applicant's summary and conclusion

Conclusions:

The 96h-LC50 value for 3-Chloro-1,2 propane diol was estimated to be 9580 mg/L using the OECD QSAR Application toolbox. Available public domain data as presented in this OECD toolbox show 24h/48h LC50 values in the same order of magnitude or higher.