Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
1-ol, [[4-[(3-aminophenyl)amino]-6-chloro-1,3,5-triazin-2-yl]amino]-2-[(E)-2-ylazo]-, polysulfonate, polynaphthen, sodium salt (1:?), diazotized, reaction products with 2-[(aminophenyl)sulfonyl]ethyl hydrogen sulfate, 1-naphthalenol, 8-amino- (1:1), polysulfonates, sodium salts and 2,4,6-trihalogeno-1,3,5-triazine
EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
The median lethal dose of FAT 40840/A TE after single oral administration to female rats, observed over a period of 14 days is:
LD50 (female rat): greater than 2000 mg/kg body weight
Key value for chemical safety assessment
Additional information
Two groups, each of three female HanRcc:WIST (SPF) rats, were treated with FAT 40840/A TE by oral gavage administration at a dosage of 2000 mg/kg body weight. The test item was diluted in vehicle (purified water) at a concentration of 0.2 g/mL and administered at a dosing volume of 10 mL/kg. The animals were examined daily during the acclimatization period and mortality, viability and clinical signs were recorded. All animals were examined for clinical signs within the first 30 minutes and approximately 1, 2, 3 and 5 hours after treatment on day 1 and once daily during test days 2-15. Mortality/viability was recorded at approximately 30 minutes, 1, 2, 3 and 5 hours after administration on test day 1 (with the clinical signs) and twice daily during days 2-15. Body weights were recorded on day 1 (prior to administration) and on days 8 and 15. All animals were necropsied and examined macroscopically. All animals survived until the end of the study period. A slightly ruffled fur was recorded in two females 3 hours post-dose and persisted up to the 5- hour reading. Soft feces were observed in all animals 5 hours after treatment. Discolorated purple feces or purple/black feces were recorded in all animals 5 hours after treatment and persisted up to test day 2. The body weight of the animals was within the range commonly recorded for this strain and age. For Group 1 no macroscopic findings were recorded at necropsy. All animals of Group 2 were found with an enlarged spleen at necropsy.
The median lethal dose of FAT 40840/A TE after single oral administration to female rats, observed over a period of 14 days is:
LD50 (female rat): greater than 2000 mg/kg body weight
Justification for classification or non-classification
FAT 40840/A E is not classified since the LC50 cut-off value for classification is 2000mg/kg
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
