Registration Dossier
Registration Dossier
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EC number: 619-590-1 | CAS number: 135302-13-5
Toxicity to aquatic plants other than algae
Administrative data
- Endpoint:
- toxicity to aquatic plants other than algae
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study according to EU/OECD guideline.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 221 (Lemna sp. Growth Inhibition Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 3-methoxy-4-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one
- EC Number:
- 619-590-1
- Cas Number:
- 135302-13-5
- Molecular formula:
- C4H7N3O2
- IUPAC Name:
- 3-methoxy-4-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Lemna gibba
- Details on test organisms:
- Lemna gibba G3
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 7 d
- Remarks on exposure duration:
- renewal of test solutions on day 4
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 7 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 95.7 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 7 d
- Dose descriptor:
- LOEC
- Effect conc.:
- > 95.7 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 7 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 95.7 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Any other information on results incl. tables
The 7-Day ErC50 was calculated as >95.7 mg a.i./L based on growth rate for both frond count and plant dry weight. The lowest observed effect concentration (LOEC) was determined as >95.7 mg a.i./L and a no observed effect concentration (NOEC) was 95.7 mg a.i./L based on both endpoints.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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