Registration Dossier
Registration Dossier
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EC number: 200-756-3 | CAS number: 71-55-6
Toxicity to reproduction
Administrative data
- Endpoint:
- two-generation reproductive toxicity
- Remarks:
- based on test type (migrated information)
- Adequacy of study:
- other information
Data source
Reference
- Title:
- No information
- Author:
- HSDB online via STN
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,1,1-trichloroethane
- EC Number:
- 200-756-3
- EC Name:
- 1,1,1-trichloroethane
- Cas Number:
- 71-55-6
- Molecular formula:
- C2H3Cl3
- IUPAC Name:
- 1,1,1-trichloroethane
- Details on test material:
- IUCLID4 Test substance: as prescribed by 1.1 - 1.4
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- Swiss
- Sex:
- male/female
Administration / exposure
Doses / concentrations
- Remarks:
- Doses / Concentrations:
0, 0.58, 1.75, or 5.83 mg/l = 0, 100, 300 or 1000 mg/kg
Basis:
Results and discussion
Overall reproductive toxicity
- Reproductive effects observed:
- not specified
Any other information on results incl. tables
RS-Freetext:
No taste aversion evident. There appeared to be no
dose-dependent effects on fertility, gestation, viability or
lactation indices. Pup survival and weight gain were not
adversely affected. No significant lethal mutations or
teratogenic effects in either of the 2 generations tested.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
