Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 603-491-5 | CAS number: 131513-00-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In an algae growth inhibition test the EC50 was 0.261 mg/L after 72 h, the EC20 was 0.152 mg/L after 72 h and the EC10 was 0.113 mg/L after 72 hours. The values are based on geometric mean measured test test item concentrations of the inhibition of growth rate.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.261 mg/L
- EC10 or NOEC for freshwater algae:
- 0.113 mg/L
Additional information
The toxicity of the test item to the unicellular freshwater green alga Desmodesmus subspicatus was determined according to the principles of OECD 201 and Council Regulation (EC) No 440/2008/ Method C.3. The aim of the study was to assess the effects on growth rate and yield over a period of 72 hours. The study was conducted under static conditions with an initial cell density of 4910 cells/mL. Based on a preliminary test, 5 concentration Ievels were tested in a geometrical series with these nominal concentrations: 0.1 - 0.32 - 1.0 - 3.2 - 10 mg/L, corresponding to geometric mean measured concentrations of 0.0440 - 0.0716 - 0.126 - 0.220 - 0.408 mg/L. Three replicates were tested for each test item concentration and six replicates for the control. Environmental conditions were determined to be within the acceptable Iimits. The concentrations of the test item were analytically verified by HPLCDAD at the start and the end of the exposure of all test concentrations and the control. The measured concentrations of the test item at the start of the exposure were in the range of 60 to 78% of the nominal values and < Iimit of quantification after 72 hours. Therefore, all effect values are based on both the nominal and the geometric mean measured concentrations of the test item. Instead of the test item, another compound with a relative retention time of 0.36 (absorption maximum 291 nm) was detected in all exposure concentrations after 72 hours. This peak was integrated. These data show that the magnitude of the exposure concentrations are also reflected by the magnitude of the areas of the metabolite. The EC50 was 0.261 after 72 h, the EC20 was 0.152 after 72 h and the EC10 was 0.113 mg/L after 72 hours. The values are based on geometric mean measured test item concentrations of the inhibition of growth rate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.