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EC number: 801-829-8 | CAS number: 1247790-47-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 6 March 2013 to 7 October 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: According to the OECD Guideline and it is GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 3,6-dimethylheptan-2-ol
- EC Number:
- 801-829-8
- Cas Number:
- 1247790-47-1
- Molecular formula:
- C9H20O
- IUPAC Name:
- 3,6-dimethylheptan-2-ol
- Details on test material:
- - Physical state: clear colorless liquid
- Storage condition of test material: room temperature in the dark
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, predominantly domestic, non-adapted
- Details on inoculum:
- A mixed population of sewage treatment micro-organisms was obtained on 14 June 2013 from the final effluent stage of the Severn Trent Water Plc sewage treatment plant at Loughborough, Leicestershire, UK, which treats predominantly domestic sewage.
The sample of effluent was filtered through coarse filter paper and maintained on aeration in a temperature controlled room at 21±1ºC prior to use. - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Details on study design:
- The test item at a concentration of 100 mg/L was exposed to sewage treatment micro-organisms with mineral medium in sealed culture vessels in diffuse light at 22±1ºC for 28 days.
The degradation of the test item was assessed by the measurement of daily oxygen consumption values on Days 0 to 28. Control solutions with inoculum and the reference item, aniline, together with a toxicity control were used for validation purposes.
Preparation of Test System:
The following test preparations were prepared and inoculated mineral medium to act as the inoculum control
a) Three replicate bottles containing inoculated mineral medium to act as the inoculum control.
b)Two replicate bottles containing inoculated mineral medium and the reference item, aniline, at a concentration of 100 mg/L.
c) Three replicate bottles containing inoculated mineral medium and the test item at a concentration of 100 mg/L.
d) Two replicate bottles containing inoculated mineral medium the reference item, aniline, at a concentration of 100 mg/L and the test item at a concentration of 100 mg/L to act as toxicity control vessels.
All vessels were inoculated with the prepared inoculum at a rate of 1% v/v.
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Value:
- 91
BOD5 / COD results
- Results with reference substance:
- Aniline (procedure control) attained 77% degradation after 14 days and 76% degradation after 28 days thereby confirming the suitability of the inoculum and test conditions.
Any other information on results incl. tables
BOD and Biodegradation Values
Sample Description | ThOD | Day 7 | Day 14 | Day 28 | |||||
BOD (mg O2/L) | Degradation (%) | BOD (mg O2/L) | Degradation (%) | BOD (mg O2/L) | Degradation (%) | Mean Biodegradation (%) | |||
Inoculum Control | R1 | - | 12,5 | - | 26,94 | - | 69,34 | ¡- | - |
R2 | - | 13,28 | - | 29,66 | - | 78,52 | - | ||
Procedure Control | 309 | 220,04 | 67 | 265,06 | 77 | 308,54 | 76 | - | |
Test Item | R1 | 292 | 22,86 | 3 | 224,36 | 67 | 320,04 | 84 | 91 |
R2 | 292 | 49,68 | 13 | 278,48 | 86 | 360,86 | 98 | ||
Toxicity Control | 601 | 207,58 | 32 | 441,78 | 69 | 543,28 | 78 | - |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The test item attained 91% degradation after 28 days and satisfied the 10 -Day window validation criterion, whereby 60% degradation must be attained within 10 days of the degradation rate exceeding 10%. The test item can therefore be considered to be readily biodegradable under the stric terms and conditions of OECD Guideline No.301F.
- Executive summary:
The study was performed to assess the ready biodegradability of the test item in an aerobic aqueous media. The method followed was designed to be compatible with the OECD Guidelines for Testing of Chemicals (1992) No. 301F, "Ready Biodegradability; Manometric Respiratory Test" refered as method C.4-D of Commission Regulation (EC) No. 440/2008.
The test item at a concentration of 100 mg/L was exposed to sewage treatment micro-organisms with mineral medium in sealed culture vessels in diffuse light at 22±1ºC for 28 days.
The degradation of test item was assessed by the measurement of daily oxygen consumption values on Days 0 to 28. Control solutions with inoculum and the reference item, aniline, together with a toxicity control were used for validation purposes.
The test item attained 91% degradation after 28 days and satisfied the 10 -Day window validation criterion, whereby 60% degradation must be attained within 10 days of the degradation rate exceeding 10%. The test item can therefore be considered to be readily biodegradable under the stric terms and conditions of OECD Guideline No.301F.
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