Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Adipic acid possesses eye and respiratory tract irritation based on the acidic character. Since disodium adipate is neutral in aqueous solutions no read-across between the disodium salt and the acid is appropriate for local effects. In vitro corrosion and irritation studies are performed for the disodium salt and indicate that this compound is not irritating. 

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Adipic acid possesses eye and respiratory tract irritation based on the acidic character. Since disodium adipate is neutral in aqueous solutions no read-across between the disodium salt and the acid is appropriate for local effects. In vitro corrosion and irritation studies are performed for the disodium salt and indicate that this compound is not irritating.

Justification for classification or non-classification

Disodium adipate is considered to be not irritating.