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EC number: 267-029-0 | CAS number: 67762-64-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The results of four studies indicate that the read-across substance, decanoic acid, ester with 2-ethyl-2- (hydroxymethyl)-1,3- propanediol octanoate, would not be expected to cause acute toxicity in fish at its water saturation limit or water solubility limit. Therefore, by read-across, heptanoic acid, ester with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol pentanoate is not expected to cause acute toxicity in fish. As a worst case, the lowest LC50 value for freshwater fish was selected as the value used for the CSA.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 1 000 mg/L
Marine water fish
Marine water fish
- Effect concentration:
- 5 045 mg/L
Additional information
Three studies, investigating the short-term toxicity to freshwater fish of read-across substance, decanoic acid, ester with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol octanoate, were conducted. The first study conducted according to OECD Guideline 203 determined a LL50 (96 h) > 10000 mg/L (WAF loading rate). In the second study with Salmo trutta conducted according to OECD Guideline 203 the EC50 (96 h) is > 1000 mg/L and the LOEC > 1000 mg/L. As at the two highest concentrations (320 and 1000 mg/L) a small amount of emulsion and some increase in turbidity was observed, the highest concentration (1000 mg/L) demonstrated a worst case.
In the third study with Oncorhynchus mykiss, the 96-h LC50 was >1035 mg/L (nominal concentration, oil in water suspension/dispersion). Nominal test concentrations were all above the water solubility of the test material (experimentally determined to be 0.48 mg/L). GC-FID analysis revealed that test material was present in water samples and this is not unexpected since test material was mechanically dispersed in water. In all 3 studies no mortality was observed at the water solubility limit of the test substance.In addition, an acute fish toxicity study with a saltwater fish (Cyprinodon variesatus) was conducted with read-across substance, decanoic acid, ester with 2-ethyl-2- (hydroxymethyl)-1,3-propanediol octanoate, in accordance with EU Method C.1 with deviations (no chemical analysis was carried out on the tested water solutions). The 96-h LC50 was > 5045 mg/L (nominal concentration, oil in water suspension/dispersion).
In conclusion, these studies indicate that the read-across substance, decanoic acid, ester with 2-ethyl-2- (hydroxymethyl) -1,3- propanediol octanoate, would not be expected to cause acute toxicity in fish at its water saturation limit or water solubility limit. Therefore, by read-across, heptanoic acid, ester with 2-ethyl-2-(hydroxymethyl) -1,3-propanediol pentanoate is not expected to cause acute toxicity in fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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