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EC number: 203-528-1 | CAS number: 107-87-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2013 May
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- other: Photocell BP detection method, Vapor Pressure Curve
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 3 206 Pa
- Conclusions:
- The vapor pressure of the test substance was determined to be 3206 Pa at 20 C.
- Executive summary:
The vapor pressure of the test substance was determined to be 3206 Pa at 20 C.
Reference
*INFORMATION REQUIRMENTS-The study does not need to be conducted if the melting point is above 300C. If the melting point is between 200C and 300C, a limit value based on measurement or a recognized calculation method is sufficient. Vapor pressure testing is also not required for chemicals with a standard boiling point of <30C, as these substances will have vapor pressures above the limit of measurement. (105Pa)
METHOD
The vapor pressure measurements were conducted using a photocell detection method which employs a Mettler FP90 temperature control module and a Mettler FP81HT measurement cell. The tests were conducted according to Method A2 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
PROCEDURE
A reference material, m-xylene, was first run to confirm the accuracy of the method. In Table VII-1, the measured vapor pressure data of m-xylene are compared to recommended literature vapor pressure data from Reference VII-1.
The sample was placed in a glass boiling point tube to height of 15 mm. A boiling point capillary was then inserted to act as a boiling chip. The sample temperature was controlled by the FP90/FP81HT system as was the detection of the boiling point of the sample. Pressure was regulated by a manifold consisting of stainless steel tubing, two manometers, vacuum pump, a surge tank, and a bleed valve. The vacuum apparatus was connected to the glass sample tube via a short section of silicone tubing. The pressure was then set to the desired value and allowed to stabilize. The sample temperature was then raised slowly to a value approximately 30 ⁰C below the expected boiling point. The sample was then allowed to degas at constant temperature for 5 minutes . The measurement of the boiling point at stated pressure was then determined by increasing the sample temperature at a rate of 1 ⁰C/minute until the instrument detected boiling of the sample. Boiling was optically detected by a photocell in the FP81HT. The boiling point is defined as the point when the bubble rate in the sample tube reaches 0.6 Hz.
CALCULATIONS
The measured data were regressed to an Antoine equation and the vapor pressure at 20 ⁰C calculated from the resulting equation (Figure VII-1).
RESULTS/CONCLUSION
The MPK raw measured data are reported in Table VII-2. The Method A4 estimated value of vapor pressure at 20 °C is 3280 Pa versus the extrapolated value of 3206 Pa. The greatest value of vapor pressure, 3206 Pa, between these two values is reported as the vapor pressure of MPK at 20 °C since it is the most conservative.
Table VII-1. m-Xylene reference vapor pressure measurements
Measured Reference Deviation from
Temp, °C Pressure, mm Hg Pressure, mm Hg Reference, mm Hg
44.5 20 23.9 -3.9
57.0 40 43.3 -3.3
72.6 80 84.5 -4.5
89.8 162 163.5 -1.5
109.7 333 321.6 11.4
139.4 760 766.2 -6.2
Table VII-2. MPK vapor pressure measurements
Temp, ⁰C Pressure, mm Hg Pressure, Pa
29.2 40 5333
42.5 80 10666
58.3 159 21198
77.1 329 43863
102.7 760 101325
Figure VII-1. Regression of measured vapor pressure data
FigureVII-2. Plot of measured vapor pressure and estimated vapor pressure at 20°C
Figure VII-3. Estimation of Vapor Pressure at 20 ⁰C from Normal Boiling Point
Figure VII-3. Estimation of Vapor Pressure at 20 ⁰C from Normal Boiling Point (continued)
REFERENCES
VII-1. Design Institute for Physical Properties (DIPPR) 801 Thermophysical Property Database, Sponsors’ Version, January 2011.
VII-2. W. J. Lyman, W. F. Reehl, and D. H. Rosenblatt,Handbook of
Chemical Property Estimation Methods, McGraw-Hill,
1982.
Description of key information
The vapor pressure of the test substance was determined to be 3206 Pa at 20 C.
Key value for chemical safety assessment
- Vapour pressure:
- 3 206 Pa
- at the temperature of:
- 20 °C
Additional information
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