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Diss Factsheets
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EC number: 212-390-1 | CAS number: 813-93-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Study period:
- Not specified
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to OECD 302B test guideline but full details are not available.
- Justification for type of information:
- The citrate component of bismuth citrate has a very similar structure to citric acid therefore a read-across approach is considered to be justified.
The concept of ready biodegradability does not apply to the bismuth component of bismuth citrate. - Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
None - Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: 1 g sludge/litre
- Details on inoculum:
- None
- Duration of test (contact time):
- 14 d
- Initial conc.:
- ca. 400 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- No data
- Reference substance:
- other: no data
- Preliminary study:
- No data
- Test performance:
- No data
- Parameter:
- % degradation (DOC removal)
- Value:
- 85
- Sampling time:
- 14 d
- Details on results:
- A DOC removal of 85% citiric acid was obtained after 1 day.
- Results with reference substance:
- No data
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- An inherent biodegradation value of 85% after 1 day in 14 days have been determined for Citric acid in a test conducted according to OECD Guideline 302B.
- Executive summary:
An inherent biodegradation value of 85% after 1 day in 14 days have been determined for read-across substance, citric acid, in a test conducted in accordance with OECD Guideline 302B.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- Not specified
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to the OECD 301B test guideline, however, full details of the study are not available.
- Justification for type of information:
- The citrate component of bismuth citrate has a very similar structure to citric acid therefore a read-across approach is considered to be justified.
The concept of ready biodegradability does not apply to the bismuth component of bismuth citrate. - Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No data - Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: Effluents after acclimation
- Details on inoculum:
- No data
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 10 mg/L
- Based on:
- test mat.
- Details on study design:
- No data
- Reference substance:
- other: No data
- Preliminary study:
- No data
- Test performance:
- No data
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 97
- Sampling time:
- 28 d
- Details on results:
- No data
- Results with reference substance:
- No data
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- A ready biodegradation value of 97% has been determined for Citric acid in a test conducted according to OECD Guideline 301 B.
- Executive summary:
- A ready biodegradation value of 97% has been determined for read-across substance, citric acid, in a test conducted according to OECD Guideline 301 B.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to OECD 301E test guideline, however, complete details are not provided.
- Justification for type of information:
- The citrate component of bismuth citrate has a very similar structure to citric acid therefore a read-across approach is considered to be justified.
The concept of ready biodegradability does not apply to the bismuth component of bismuth citrate. - Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- Deviations:
- yes
- Remarks:
- In order to maintain an optimal C:N:P ratio, ammonium concentration specified in the OECD procedure was tripled.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No data - Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: The inoculum 0.05% effluent
- Details on inoculum:
- No data
- Duration of test (contact time):
- 19 d
- Initial conc.:
- 320 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- Composition of medium: To maintain an optimal C:N:P ratio, the ammonium concentration specified in the OECD procedure was tripled. In addition, a trace metal and an essential vitamin solution was added to optimize the test conditions.
- Reference substance:
- other: No data
- Preliminary study:
- No data
- Test performance:
- No data
- Parameter:
- % degradation (DOC removal)
- Value:
- 100
- Sampling time:
- 19 d
- Details on results:
- No data
- Results with reference substance:
- No data
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- A ready biodegradation value of 100% in 19 days have been determined for Citric acid in a test conducted according to OECD 301E. The result is considered reliable.
- Executive summary:
- A ready biodegradation value of 100% in 19 days have been determined for read-across substance, citric acid in a test conducted according to OECD Guideline 301E.
Referenceopen allclose all
Description of key information
Three studies conducted according to different OECD Guidelines found read-across substance, citric acid, to be readily biodegradable therefore, by read-across the citrate component of bismuth citrate is considered to be biodegradable. The concept of ready biodegradabiity does not apply to the bismuth component of bismuth citrate.
Key value for chemical safety assessment
Additional information
Three studies conducted according to different OECD Guidelines found read-across substance, citric acid, to be readily biodegradable. The citrate component of bismuth citrate has a very similar structure to citric acid therefore a read-across approach is considered to be justified.
The concept of ready biodegradability does not apply to the bismuth component of bismuth citrate.
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