Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 938-754-6 | CAS number: -
Dissociation constant
Administrative data
Link to relevant study record(s)
Description of key information
The assessment of pKa of the registered substance is complicated. As the substance contains ionisable components (unreacted fatty acids), the pKa values for these are given. To obtain the dissociation constants of the fatty acids Lauric acid, Myristic acid, Palmitic acid and Stearic acid a HSDB database search was performed. These are weak acids with pKa values of 5.3 (Lauric acid), 4.9 (Myristic acid), 4.75 (Palmitic acid) and 4.75 (Stearic acid). For the other components of Sucroglyceride C12-18, C18unsatd. the dissociation constants were estimated using SPARC on-line calculator v4.6. For Sucrose, Glycerol, monoglyceride C12, monoglyceride C14, monoglyceride C16 and monoglyceride C18 pKa values > 10 were obtained by calculation, indicating that at environmentally relevant pH no dissociation occurs. The value used for chemical safety assessment is the pKa of Lauric acid (5.3) being the major ionisable component.
Key value for chemical safety assessment
- pKa at 20°C:
- 5.3
Additional information
Sucroglyceride C12-18, C18unsatd. is a complex reaction product of partial esters of glycerol and sucrose with fatty acids and unreacted glycerol, fatty acids and sucrose. The assessment of pKa of the registered substance is complicated. As the substance contains ionisable components (unreacted fatty acids), the pKa values for these are given.
To obtain the dissociation constants of the fatty acids Lauric acid, Myristic acid, Palmitic acid and Stearic acid a HSDB database search was performed. These are weak acids with pKa values of 5.3 (Lauric acid), 4.9 (Myristic acid), 4.75 (Palmitic acid) and 4.75 (Stearic acid).
For the other components of Sucroglyceride C12-18, C18unsatd. the dissociation constants were estimated using SPARC on-line calculator v4.6.
For Sucrose, Glycerol, monoglyceride C12, monoglyceride C14, monoglyceride C16 and monoglyceride C18 pKa values > 10 were obtained by calculation, indicating that at environmentally relevant pH no dissociation occurs.
The value used for chemical safety assessment is the pKa of Lauric acid (5.3) being the major ionisable component.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
