Registration Dossier
Registration Dossier
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EC number: 211-059-9 | CAS number: 628-89-7
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Journal of Industrial Hygiene and Toxicology
- Author:
- JIHTAB
- Year:
- 1 944
- Bibliographic source:
- Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49.
- Reference Type:
- review article or handbook
- Title:
- DPIM : DKN000
- Author:
- Richard J. Lewis, Sr.
- Year:
- 2 007
- Bibliographic source:
- SAX (Sax's Handbook of Dangerous Industrial Materials); Journal of Industrial Hygiene and Toxicology. 26 (1944), 269
- Reference Type:
- review article or handbook
- Title:
- RTECS Number : KK1350000
- Author:
- RTECS handbook
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances); (JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944)
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from SAX and RTECS
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 2-(2-chloroethoxy)ethanol
- EC Number:
- 211-059-9
- EC Name:
- 2-(2-chloroethoxy)ethanol
- Cas Number:
- 628-89-7
- Molecular formula:
- C4H9ClO2
- IUPAC Name:
- 2-(2-chloroethoxy)ethan-1-ol
- Details on test material:
- - Name of test material : 2-(2-chloroethoxy)ethanol
- Molecular formula : C4H9ClO2
- Substance type: Organic
- Physical state: Liquid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 6 300 other: mg/kg
- Based on:
- test mat.
- Remarks on result:
- other: Details of toxic effects not reported other than lethal dose value
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- This value suggest that the chemical 2-(2-chloroethoxy)ethanol does not exhibit acute toxicity through the oral route
- Executive summary:
Acute oral toxicity value of 2-(2-chloroethoxy)ethanol in rat was found to be LD50 :6300 mg/kg. This value suggests that the chemical 2-(2-chloroethoxy)ethanol does not exhibit acute toxicity through the oral route for classification as for classification the lethal dose should be less than 2000 mg/kg.
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