Registration Dossier
Registration Dossier
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EC number: 204-287-5 | CAS number: 118-92-3
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (LLNA)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: only data in tabular form available
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- National Institute of Environmental Health Studies
- Year:
- 2 007
- Bibliographic source:
- ICCVAM Test Method Evaluation Report Appendix D, Annex III
- Report date:
- 2007
Materials and methods
- Principles of method if other than guideline:
- no details described about performed LLNA test
- GLP compliance:
- not specified
- Type of study:
- mouse local lymph node assay (LLNA)
Test material
- Reference substance name:
- Anthranilic acid
- EC Number:
- 204-287-5
- EC Name:
- Anthranilic acid
- Cas Number:
- 118-92-3
- Molecular formula:
- C7H7NO2
- IUPAC Name:
- 2-aminobenzoic acid
- Details on test material:
- no detailed information
Constituent 1
In vivo test system
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Study design: in vivo (LLNA)
- Vehicle:
- acetone/olive oil (4:1 v/v)
- Concentration:
- 10, 25 and 20%
Results and discussion
In vivo (LLNA)
Results
- Parameter:
- SI
- Remarks on result:
- other: Conc. 10%: SI 0.90 Conc. 25%: SI 1.10 Conc. 50%: SI 1.40 EC3 value not calculated because no SI value was >=3
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information
- Conclusions:
- The substance 2-aminobenzoic acid is not a skin sensitizer
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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