Registration Dossier
Registration Dossier
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EC number: 223-772-2 | CAS number: 4065-45-6
Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- density, other
- Remarks:
- density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Experimental tests performed using standard test guidelines
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Qualifier:
- according to guideline
- Guideline:
- other: method recommended in the International Pharmacopoeia, fourth Edition, 2014.
- GLP compliance:
- no
- Type of method:
- pour and tap (for solids)
- Key result
- Type:
- pour density
- Density:
- 0.298 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: pressure - 973.4 hPa
- Key result
- Type:
- tap density
- Density:
- 0.315 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: pressure - 973.4 hPa
- Conclusions:
- The mean pour density and tapped density of test chemical was determined to be 0.2977 g/cm³ and 0.3152 g/cm³at 20°C and 973.4 hPa.
- Executive summary:
The density of test chemical was determined following OECD guideline 109 and according to the method recommended in the
International Pharmacopoeia, fourth Edition, 2014. The mean pour density and tapped density of the test item was determined to be 0.2977 g/cm³ and 0.3152 g/cm³at 20°C and 973.4 hPa.
Reference
| Parameters | Details | Calculated values | Average Density | |
|
1st Calculation | 2nd Calculation | ||
Pour Density of test Item (g/cm³) |
= m/V |
0.3086 |
0.2868 |
0.2977 |
Tap density of test Item (g/cm³) |
= m V1 |
0.3268 |
0.3036 |
0.3152 |
Description of key information
The density of test chemical was determined following OECD guideline 109 and according to the method recommended in the
International Pharmacopoeia, fourth Edition, 2014. The mean pour density and tapped density of the test item was determined to be 0.2977 g/cm³ and 0.3152 g/cm³at 20°C and 973.4 hPa.
Key value for chemical safety assessment
- Relative density at 20C:
- 0.298
Additional information
The density of test chemical was determined following OECD guideline 109 and according to the method recommended in the
International Pharmacopoeia, fourth Edition, 2014. The mean pour density and tapped density of the test item was determined to be 0.2977 g/cm³ and 0.3152 g/cm³at 20°C and 973.4 hPa.
From other experimental report,bulk density of test chemical was determined to be 0.587 g/cm3 at 22degC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
