Registration Dossier
Registration Dossier
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EC number: 816-285-7 | CAS number: 1263133-33-0
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- other: Shake flask method
- Key result
- Water solubility:
- 0.23 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 100 other: mL
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- 6.41
- Details on results:
- The mean pH of the test item solution in all the solvents measured during each sampling occasion (24, 48 and 72 hours) was found to be 6.39, 6.42 and 6.43, respectively.
The mean maximum and minimum temperature of orbital shaking incubator maintained at 30 ± 1°C was 30.2°C and 29.7°C, respectively. The mean maximum and minimum temperature of incubator maintained at 20 ± 0.5°C were 20.3°C and 20.0°C, respectively. - Conclusions:
- Water solubility: 0.23 ± 0.01 g/L at 20 ± 0.5°C
- Executive summary:
This study was conducted to determine the water solubility of the test substance. The water solubility was determined according to regulatory guidelines OECD 105, OPPTS 830.7840 and EEC method A.6. The solubility of the test substance was studied in double distilled water at 20 ± 0.5°C, using the shake flask method. The samples were analysed by high-performance liquid chromatography.
Mean water solubility of the test substance in double distilled water was 0.23 ± 0.01 g/L at 20 ± 0.5°C.
Reference
Description of key information
OECD Guideline 105
Key value for chemical safety assessment
- Water solubility:
- 0.23 g/L
- at the temperature of:
- 20 °C
Additional information
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