Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-019-7 | CAS number: 7783-66-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
- Endpoint:
- toxicity to soil microorganisms
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Available ecotoxicity data on (hydrogen) fluoride up to 1998 was reviewed and summarised by the European Chemicals Bureau (ECB). Although detail on design and methodology is very limited in this report, endpoints and conclusions are considered suitably reliable for environmental risk assessment as the substance was assessed as part of the EU-RAR and in accordance with Council Regulation (EEC) 793/93 on the evaluation and control of risks of existing substances.
Data source
Reference
- Reference Type:
- publication
- Title:
- European Union Risk Assessment Report - Hydrogen Fluoride
- Author:
- Institute for Health and Consumer Protection, European Chemicals Bureau.
- Year:
- 2 001
- Bibliographic source:
- European Chemicals Bureau Existing Substances, 1st priority list, no. 8
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The EU-RAR summarises a number of both possible guideline and non-guideline studies. Details on design and methodology are however not provided.
- GLP compliance:
- no
Test material
- Reference substance name:
- Sodium fluoride
- EC Number:
- 231-667-8
- EC Name:
- Sodium fluoride
- Cas Number:
- 7681-49-4
- IUPAC Name:
- sodium fluoride
- Test material form:
- not specified
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 63 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 106 other: mg/kg (dry/wet unspecified)
- Nominal / measured:
- not specified
- Conc. based on:
- other: Fluoride
- Basis for effect:
- nitrate formation rate
- Duration:
- 63 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 340 other: mg/kg (dry/wet unspecified)
- Nominal / measured:
- not specified
- Conc. based on:
- other: Fluoride
- Basis for effect:
- other: NH4-mineralisation
- Duration:
- 63 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1 060 other: mg/kg (dry/wet unspecified)
- Nominal / measured:
- not specified
- Conc. based on:
- other: Fluoride
- Basis for effect:
- other: P-mineralisation
- Duration:
- 24 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 3 000 other: mg/kg (dry/wet unspecified)
- Nominal / measured:
- not specified
- Conc. based on:
- other: fluoride
- Basis for effect:
- other: Dehydrogenase inhibition
- Details on results:
- The dehydrogenase assay was carried out with sodium fluoride, the other studies with potassium fluoride.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The NOEC values for soil microbial processes range from 106-300 mg/kg. Nitrification was found to be the most sensitive endpoint. The NOEC of 106 mg/kg was used in the EU-RAR for determination of the PNECsoil.
- Executive summary:
The EU RAR reviews and summarises the available data on the toxicity of sodium and potassium fluoride to terrestrial microorganisms. The NOEC values (expressed in terms of fluoride ion, F-) are reported to range from 106 to 3000 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.