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Diss Factsheets
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EC number: 231-104-6 | CAS number: 7439-95-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Magnesium is a cofactor of many enzymes involved in intermediary metabolism. Magnesium is absorbed in the intestinal tract and excreted into the digestive tract by bile and pancreatic and intestinal juices. There is an apparent obligatory urinary loss of magnesium, which amounts to about 12 mg/day and the urine is the major route of excretion under normal conditions. Unabsorbed magnesium is excreted in the feces.. Magnesium is filtered by the glomeruli and reabsorbed by renal tubules. In the blood plasma, about 65 percent is the ionic form while the remainder is bound to protein. Excretion also occurs via the sweat and milk. Approximately 70 percent of serum magnesium is ultrafilterable, and about 95 percent of the filtered magnesium is reabsorbed, which is an important factor in maintaining magnesium homeostasis. Tissue distribution studies indicate that of 20 g body burden in humans, the majority is intracellular in the bone and muscle including the myocardium, but some magnesium is present in every cell of the body.
Additional information
Magnesium is a cofactor of many enzymes involved in intermediary metabolism. Magnesium is absorbed in the intestinal tract and excreted into the digestive tract by bile and pancreatic and intestinal juices. There is an apparent obligatory urinary loss of magnesium, which amounts to about 12 mg/day and the urine is the major route of excretion under normal conditions. Unabsorbed magnesium is excreted in the feces.. Magnesium is filtered by the glomeruli and reabsorbed by renal tubules. In the blood plasma, about 65 percent is the ionic form while the remainder is bound to protein. Excretion also occurs via the sweat and milk. Approximately 70 percent of serum magnesium is ultrafilterable, and about 95 percent of the filtered magnesium is reabsorbed, which is an important factor in maintaining magnesium homeostasis. Tissue distribution studies indicate that of 20 g body burden in humans, the majority is intracellular in the bone and muscle including the myocardium, but some magnesium is present in every cell of the body.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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