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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 908-820-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Information from TSCA 8e section; no full report in hand but result has impact on hazardous properties and classification and labelling of test material
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 995
- Report date:
- 1995
Materials and methods
Test material
- Reference substance name:
- Reaction mass of (E)-1-chlorobut-2-ene and 3-chlorobut-1-ene
- EC Number:
- 908-820-9
- Molecular formula:
- not applicable
- IUPAC Name:
- Reaction mass of (E)-1-chlorobut-2-ene and 3-chlorobut-1-ene
- Details on test material:
- A mixture of approx. 50:50 1-chloro-2-butene and 3-chloro-1-butene were tested.
Constituent 1
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- 16.3 mg/L air (analytical)
- Other findings:
- - Potential target organs: CNS
Any other information on results incl. tables
2/6 animals died in the 2990 ppm group, 3/6 in the 4410 ppm and 5/6 in the 6290 ppm group. (LC50 ca. 4410 ppm) Clinical signs: Impairment of startle response from 359 ppm. At 2990 and 4410 ppm abnormal gait, impaired mobility, changes in arousal, hunched posture, irregular respiration. Approximate LC50 in mg/l: 4410 ppm * 90.55/24.45 * 1000 = 16.3 mg/l
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Remarks:
- Migrated information
- Conclusions:
- 2/6 animals died in the 2990 ppm group, 3/6 in the 4410 ppm and 5/6 in the 6290 ppm group. (LC50 ca. 4410 ppm)
Clinical signs: Impairment of startle response from 359 ppm. At 2990 and 4410 ppm abnormal gait, impaired mobility, changes in arousal, hunched posture, irregular respiration. Approximate LC50 in mg/l: 4410 ppm * 90.55/24.45 * 1000 = 16.3 mg/l
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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