4-(2-chlorophenyl)-N-cyclohexyl-N-ethyl-5-oxo-4,5-dihydro-1H-tetrazole-1-carboxamide

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Feb 22 1995 - May 6 1996

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

extrapolated data

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

other: OECD 104

Principles of method if other than guideline:

Calculation of the Boiling Point from the results of the vapour pressure determinations

GLP compliance:

yes

Type of method:

other: saturation method

Decomposition:

yes

Decomp. temp.:

> 180 °C

A boiling point of YRC 2388 cannot be determined experimentally due to the thermal instability under the conditions of the determination. Extrapolating the vapour pressure curve gives as a result a boiling point well above 180 °C which is a temperature range where decomposition reactions occur according to thermal stability studies.

From the experimental values measured between 40 and 60 °C the boiling point was calculated by extrapolation according to the Clausius -Clapeyron equation: log p = A + B / T.

With regression coefficients A and B calculated by nonlinear regression to be 16.9833 and -7698.56, respectively the temperature corresponding to a vapour pressure of 1013 hPa was found to be 280 °C.

Description of key information

Boiling point > 180 °C (Extrapolated from the vapour pressure curve)

Additional information

A boiling point cannot be determined experimentally due to the thermal instability under the conditions of the determination. Extrapolating the vapour pressure curve gives as a result a boiling point of 280 °C, well above 180 °C, which is a temperature range where decomposition reactions occur according to thermal stability studies.