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EC number: 257-048-2 | CAS number: 51200-87-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17-18 September 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Version / remarks:
- 1996
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Version / remarks:
- EC No. 440/2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Version / remarks:
- 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- 4,4-dimethyloxazolidine
- EC Number:
- 257-048-2
- EC Name:
- 4,4-dimethyloxazolidine
- Cas Number:
- 51200-87-4
- Molecular formula:
- C5H11NO
- IUPAC Name:
- 4,4-dimethyl-1,3-oxazolidine
- Reference substance name:
- 2,3-dimethyl-1,3-oxazinane
- Cas Number:
- 31951-99-2
- Molecular formula:
- C6H13NO
- IUPAC Name:
- 2,3-dimethyl-1,3-oxazinane
- Reference substance name:
- 3,5,5-trimethylmorpholin-2-one
- Cas Number:
- 57765-62-5
- Molecular formula:
- C7H13NO2
- IUPAC Name:
- 3,5,5-trimethylmorpholin-2-one
- Test material form:
- liquid
- Details on test material:
- Lot no. MA20190405
Test item storage 2–8 °C, protected from light
Constituent 1
impurity 1
impurity 2
- Specific details on test material used for the study:
- Batch No.: MA20190405
Storage: Refrigerator (approx. 2-8°C)
Results and discussion
Boiling point
- Key result
- Boiling pt.:
- >= 129 - <= 131 °C
- Atm. press.:
- 1 013 hPa
- Decomposition:
- no
Any other information on results incl. tables
The results of the DSC-measurements are given in the table below:
Measurement No. |
Sample weight / mg |
Onset of Effect / °C |
Range of effect / °C |
Weight loss / mg |
Atmospheric pressure / hPa |
PN20209 |
9.31 |
131.10 |
40 – 170 (endo) |
9.31 |
1023.0 |
PN20210 |
9.70 |
129.82 |
40 – 160 (endo) |
9.70 |
1023.0 |
During the heating phase a distinct endothermic effect was observed in the temperature range of 40-170°C, which can be assigned to the boiling of the test item.
For the correction of the boiling temperature to standard pressure the test item was assigned to chemical group 3 (e.g. amines). A correction value f = 5.05 was used for the temperature of 130 °C.
The lowest measured onset temperature is corrected to standard pressure to be 129.49 °C and the highest onset temperature to be 130.77 °C. As the corrected onset temperatures in both tests deviate by more than 0.5 K from their mean value of 130.13 °C, the test item has a boiling range of 129 – 131 °C.
Applicant's summary and conclusion
- Conclusions:
- The test item 4,4-dimethyloxazolidine (CAS no. 51200-87-4) has a boiling range of
129 – 131 °C at standard pressure (1013 hPa) as determined by Differential Scanning Calorimetry according to Regulation (EC) No. 440/2008 Method A.2. and OECD Test Guideline 103 (1995). - Executive summary:
The test item 4,4-dimethyloxazolidine (CAS no. 51200-87-4) has a boiling range of
129 – 131 °C at standard pressure (1013 hPa) as determined by Differential Scanning Calorimetry according to Regulation (EC) No. 440/2008 Method A.2. and OECD Test Guideline 103 (1995).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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